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I. Mitosis

I. Mitosis. Happy Halloween! . Why do animals shed their skin?. A. Asexual Reproduction. When do cells use it? ____________ ____________ ____________ Cell that reproduce by asexual reproduction reproduce constantly. . B. Mitosis = Asexual Reproduction.

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I. Mitosis

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  1. I. Mitosis Happy Halloween! 

  2. Why do animals shed their skin?

  3. A. Asexual Reproduction • When do cells use it? • ____________ • ____________ • ____________ • Cell that reproduce by asexual reproduction reproduce constantly.

  4. B. Mitosis = Asexual Reproduction • Division of ______________________(body) • Process in which the nucleus divides to form 2 new nuclei Daughter Cells Somatic Cell Performed by a single (parent) cell

  5. C. PURPOSE OF MITOSIS: 1. TO PRODUCE TWO NEW NUCLEI WITH… a. ____________ ____________ b. ___________________________ . . . OF CHROMOSOMES AS THE PARENT CELL.

  6. D. What are Chromosomes? • ____________ structure of DNA in the cell • Located in the ____________ • Usually are uncoiled in the form of ____________ • Only ____________ when the cell divides and the chromatin condenses • Held together by a ____________

  7. E. 5 Stages (do not write) Interphase Prophase Metaphase Anaphase Telophase **Animated Video**

  8. 1. Interphase • Prior & After Mitosis • ____________ ____________ • ____________ % of cell life spent here • Cell goes about it’s business • ____________ ____________ • DNA is duplicated • ____________ ____________ • Cell prepares to divide • Cannot see DNA- uncoiled as ____________

  9. 2. Prophase • DNA becomes ____________ as ____________ • Nuclear membrane ____________ • ____________ migrate to opposite poles • Spindle fibers ____________ Easy to remember- Prophase- prepares for mitosis

  10. 3. Metaphase • Spindle fibers ____________ to centromeres • Chromosomes ____________ at midline of the cell Easy to remember- metaphase, DNA at middle

  11. 4. Anaphase • Spindle fibers ____________ centromeres • One chromatid goes to each ____________ (they look like V’s) Easy to remember- anaphase, away they go

  12. 5. Telophase • Chromatids reach ____________ • Mitosis ends when new ____________ ____________form • Some evidence of cell dividing Easy to remember- telophase, terminal phase

  13. 6. Last part- Cytokinesis • Division of ____________ • Technically not in mitosis • Animal cell- pinching of cell membrane- cleavage • Plant cell- formation of new cell wall- cell plate • DNA becomes non-visible, back to chromatin • Daughter cells enter G1 period of interphase

  14. What Kind of Cells Does Mitosis Produce? • Cells with a complete set of chromosomes called diploids • Humans have 46 chromosomes or 23 pairs of chromosomes • Human diploid # = 23 • Most cells are diploid

  15. Cancer • Uncontrollable mitosis (no G1) • Cells cease to do what they are supposed to be doing in favor of dividing. • Cancer does not “poison” your body…

  16. Henrietta Lacks • 1951, a poor 31 Year old African American mother of 4 was dying of cervical cancer @ Johns Hopkins Hospital • Dr. George Gey- sampled some of the cancerous cells, found they could live indefinitely and multiply outside the body • She died 6 months later, but cells still live on • HeLa cells • Used to study many different diseases • Polio Vaccine • How to transport cells

  17. The Mitosis Shuffle!  • First, lets watch: University of Madison Mitosis Shuffle • Your turn! “The Hustle” by Van McCoy

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