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Learn about mitosis, asexual reproduction, and chromosome structures in cells through an interactive animated video. Understand stages like Interphase, Prophase, Metaphase, Anaphase, Telophase, and the importance of mitosis in producing new cells. Discover how cancer impacts cell division and the fascinating story of Henrietta Lacks' immortal cells. Additionally, get groovy with "The Mitosis Shuffle" and join the fun!
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I. Mitosis Happy Halloween!
A. Asexual Reproduction • When do cells use it? • ____________ • ____________ • ____________ • Cell that reproduce by asexual reproduction reproduce constantly.
B. Mitosis = Asexual Reproduction • Division of ______________________(body) • Process in which the nucleus divides to form 2 new nuclei Daughter Cells Somatic Cell Performed by a single (parent) cell
C. PURPOSE OF MITOSIS: 1. TO PRODUCE TWO NEW NUCLEI WITH… a. ____________ ____________ b. ___________________________ . . . OF CHROMOSOMES AS THE PARENT CELL.
D. What are Chromosomes? • ____________ structure of DNA in the cell • Located in the ____________ • Usually are uncoiled in the form of ____________ • Only ____________ when the cell divides and the chromatin condenses • Held together by a ____________
E. 5 Stages (do not write) Interphase Prophase Metaphase Anaphase Telophase **Animated Video**
1. Interphase • Prior & After Mitosis • ____________ ____________ • ____________ % of cell life spent here • Cell goes about it’s business • ____________ ____________ • DNA is duplicated • ____________ ____________ • Cell prepares to divide • Cannot see DNA- uncoiled as ____________
2. Prophase • DNA becomes ____________ as ____________ • Nuclear membrane ____________ • ____________ migrate to opposite poles • Spindle fibers ____________ Easy to remember- Prophase- prepares for mitosis
3. Metaphase • Spindle fibers ____________ to centromeres • Chromosomes ____________ at midline of the cell Easy to remember- metaphase, DNA at middle
4. Anaphase • Spindle fibers ____________ centromeres • One chromatid goes to each ____________ (they look like V’s) Easy to remember- anaphase, away they go
5. Telophase • Chromatids reach ____________ • Mitosis ends when new ____________ ____________form • Some evidence of cell dividing Easy to remember- telophase, terminal phase
6. Last part- Cytokinesis • Division of ____________ • Technically not in mitosis • Animal cell- pinching of cell membrane- cleavage • Plant cell- formation of new cell wall- cell plate • DNA becomes non-visible, back to chromatin • Daughter cells enter G1 period of interphase
What Kind of Cells Does Mitosis Produce? • Cells with a complete set of chromosomes called diploids • Humans have 46 chromosomes or 23 pairs of chromosomes • Human diploid # = 23 • Most cells are diploid
Cancer • Uncontrollable mitosis (no G1) • Cells cease to do what they are supposed to be doing in favor of dividing. • Cancer does not “poison” your body…
Henrietta Lacks • 1951, a poor 31 Year old African American mother of 4 was dying of cervical cancer @ Johns Hopkins Hospital • Dr. George Gey- sampled some of the cancerous cells, found they could live indefinitely and multiply outside the body • She died 6 months later, but cells still live on • HeLa cells • Used to study many different diseases • Polio Vaccine • How to transport cells
The Mitosis Shuffle! • First, lets watch: University of Madison Mitosis Shuffle • Your turn! “The Hustle” by Van McCoy