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Explore the complex systems and changes required for effective policy change in malaria treatment. Addressing drug quality, standards, scalability, and cost information is crucial. Develop tools, interventions, and research standards to drive policy, improve drug quality monitoring, and influence providers. Enhance understanding of cost implications and plan research to optimize health outcomes.
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Overarching reality: POLICY CHANGE
Themes: • Complexity of systems and change • Need • Better/deeper knowledge • Standards • Scale • Importance of cost information • Policy change
What we know • Have evidence of problems, but how bad undefined (poor-quality drugs, adherence) and findings hard to generalize • Some interventions can be effective in some settings; not sure about how to generalize/do at scale/apply • Educational and feedback interventions • CBHW • Media • Policy change • Costly, complex, takes time • Need systems approach
Clear recommendations • Develop frameworks (including considerations of appropriate response) and increase support for drug quality testing, pharmacovigilance • Encourage information-sharing (?networks) among countries about drug quality, implementation experiences etc. • Use pre-packed drugs, patient and provider aids • Learn from private-sector approaches to influence providers and consumers • Urge GF and others to clarify commitment for sustainability of financing new treatment • Take a health systems approach
Need for information • Need to compile/review information: policy change, CBHW • More info about interventions with attention to scalability
Standards • Measuring resistance • Need to communicate standards (drug quality and appropriate dosing are accounted for) • Need to get people to follow existing standards • Quality assurance (of drugs, RDTs) • Sampling • Classifications: “failed”, “fake”, “counterfeit” • Measure stability under actual conditions
Research standards • Interventions • Scale • Sample size • Generalizable to at-scale interventions • Context • Test in range of settings (multi-site) • Private providers crucial (methods: beyond mystery patients) • Analysis • Need guidelines about design and (statistical) analysis of interventions to improve provider behavior
Research standards (cont’d) • Publication • Clear and full descriptions of interventions • (?Checklist of dimensions) • Panel to consider pros and cons of identification of brands/sources of failed drugs
Develop Tools • To drive/support policy • Develop “options appraisal” techniques for policy decisions • To support implementation • Better methods for drug quality monitoring, including validating simple methods that can be applied at the community level • Better biologic diagnostic techniques, including improving implementation and utilization
Improve understanding and develop interventions • Links between drug quality, use and development of resistance • Regulation/enforcement • How to improve effectiveness • Commercial market • How to influence • Private sector providers/dual providers • How to influence • CBHWs • Strategies to improve training, retention, motivation & remuneration
Cost information • Better C/E models of malaria treatment policy change (including costs of maintaining status quo) • Costs of interventions (incl policy chg) • Cost of intervention • Cost of implementing intervention • Projected costs of at-scale implementation
Plan research about policy change • To understand effects and test interventions to improve, e.g.: • Adherence • Treatment seeking (shift pub-pvt) • Health outcomes