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CELLULAR RESPIRATION. Cellular Respiration Equation: C 6 H 12 O 6 + 6O 2  6CO 2 +6H 2 O + energy. Cell Respiration – is a complex process in which cells make ATP by breaking down organic compounds The break down of organic compounds releases energy; some is used to make ATP.

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Cellular respiration

CELLULAR

RESPIRATION

Cellular Respiration – Chapter 9


Cellular respiration

Cellular Respiration – Chapter 9


Cellular respiration

  • Cell Respiration – is a complex process in which cells make ATP by breaking down organic compounds

  • The break down of organic compounds releases energy; some is used to make ATP.

Cellular Respiration – Chapter 9



Glycolysis and fermentation
Glycolysis and Fermentation:

Cell respiration begins with a biochemical pathway called glycolysis. Glycolysis makes little ATP. The products of glycolysis can then follow one of two pathways. Each pathways depends on whether there is oxygen or not.

Cellular Respiration – Chapter 9


Cellular respiration

Organic Compounds

Glycolysis

Fermentation

(Anaerobic)

Aerobic

Respiration

Oxygen Absent Oxygen Present

ATP

Cellular Respiration – Chapter 9


Glycolysis
Glycolysis

  • A pathway in which glucose a 6-carbon compound is oxidized to produce two 3-Carbon molecules of pyruvic acid. (All reactions of glycolysis occur in the cytosol of the cell.)

Cellular Respiration – Chapter 9


Cellular respiration

  • Oxidized– a reaction where a reactant loses one or more electrons, and becomes more positive

Cellular Respiration – Chapter 9


There are 4 steps to glycolysis
There are 4 steps to Glycolysis:

  • Two phosphates are added to glucose and it becomes a new 6-carbon compound

  • The 6-carbon compound splits into two 3-carbon PGAL’s

  • The two PGAL’s are oxidized and each gains a phosphate. At the same time 2 NAD molecules each gain a Hydrogen molecule.

  • The phosphates from step 1 and 3 are removed and the compound pyruvic acid is made. The 4 phosphates attach to ADP molecules and 4 molecules of ATP are made.

Cellular Respiration – Chapter 9


Cellular respiration

Cellular Respiration – Chapter 9


Cellular respiration

Cellular Respiration – Chapter 9 ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.


Fermentation
Fermentation: ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Conversion in absence of oxygen of pyruvic acid into other compounds

  • Happens in the cell’s cytosol

Cellular Respiration – Chapter 9


Lactic acid fermentation
Lactic Acid Fermentation ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Enzyme converts pyruvic acid into another 3-carbon compound, called lactic acid

  • 2 hydrogen (H) atoms from NADH and H add to pyruvic acid to make the final product of lactic acid

Cellular Respiration – Chapter 9


Examples of lactic acid
Examples of Lactic Acid: ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

Plays a role in food production

  • Yogurt and cheese made because of the fermentation of microorganismsOccurs in muscle cells

  • Strenuous exercise – muscles use the oxygen faster than it’s delivered. Muscles turn to lactic acid fermentation, cells build up with the acid

  • Results in muscle fatigue, pain, and cramps

Cellular Respiration – Chapter 9


Alcoholic fermentation
Alcoholic Fermentation ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Converts pyruvic acid into ethyl alcohol

  • Carbon dioxide is removed from pyruvic acid leaving a 2-carbon compound.

  • Hydrogen atoms are added to the 2-carbon compound resulting in ethyl alcohol.

Cellular Respiration – Chapter 9


Examples of alcoholic fermentation
Examples of Alcoholic Fermentation: ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Wine and beer

    • Yeast cells are added to the fermentation mixture to produce the enzymes needed for alcoholic fermentation

    • Ethyl alcohol increases to the point where fermentation stops

    • Carbon dioxide accumulates, creates “carbonate” of the beverage

  • Bread

    • Ethyl alcohol evaporates in baking but carbon dioxide created the bubbles in the dough

Cellular Respiration – Chapter 9


Energy yield of glycolysis
Energy Yield of Glycolysis: ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Efficiency of glycolysis =Energy required to make ATP /Energy released by oxidation of glucose

  • Glycolysis is only 3.5% efficient.

  • Most of the energy that was contained in the glucose is still contained the pyruvic acid.

Cellular Respiration – Chapter 9


History
HISTORY ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • Anaerobic organisms evolved very early in the history of life on earth.

  • Oxygen was not produced until photosynthetic organisms came along about a billion years later

  • Most anaerobic organisms are unicellular, any anaerobic multicellular organisms are very small

Cellular Respiration – Chapter 9


Aerobic respiration
Aerobic Respiration: ATP are made therefore there is a net yield of 2 ATP molecules for every molecule of glucose that is converted to pyruvic acid.

  • In most cells the pyruvic acid made in glycolysis does not go into fermentation but instead if oxygen is available the pyruvic acid enters cellular respiration.

  • There are 2 major steps to Aerobic or Cellular Respiration:

    • Krebs Cycle

    • Electron Transport Chain

Cellular Respiration – Chapter 9


Where the reactions for kreb s cycle and electron transport take place
Where the reactions for Kreb’s cycle and Electron Transport take place:

  • Prokaryotes – in the cytosol of the cell

  • Eukaryotes – inside the mitochondria

  • When the pyruvic acid enters the mitochondria it combines with a molecule called coenzyme A to form acetyl coenzyme A. (Abbreviated acetyl coA)

  • Cellular Respiration – Chapter 9


    The kreb s cycle
    The Kreb’s Cycle: Transport take place:

    • Is a biochemical pathway that breaks down acetyl CoA, producing CO2, hydrogen atoms, and ATP.

    • The person who identified the reactions that make up the cycle was Hans Krebs a German-British biochemist.

    Cellular Respiration – Chapter 9


    The krebs cycle has 5 main steps
    The Krebs Cycle has 5 main steps: Transport take place:

    • Acetyl CoA combines with oxaloacetic acid to produce citric acid

    • Citric acid releases a Carbon dioxide molecule to form a five-carbon compound

    • The five-carbon compound releases a carbon dioxide molecule to form a four-carbon compound

    • The four-carbon compound is converted into a new four-carbon compound

    • The new four-carbon compound is converted back into oxaloacetic acid

    Cellular Respiration – Chapter 9


    Krebs cycle continued
    Krebs Cycle Continued Transport take place:

    • In addition to the carbon dioxide produced, each turn of the Kreb’s cycle produces ATP, NADH, and FADH2

    • Each glucose molecule makes 2 pyruvic acid molecules in glycolysis. The 2 pyruvic acid molecules then make 2 acetyl CoA molecules (Each will go through the Kreb’s Cycle.)

    Cellular Respiration – Chapter 9


    Cellular respiration
    From the two acetyl CoA molecules in the Kreb’s Cycle these are produced (2 turns of the Kreb’s Cycle):

    • 6 NADH

    • 2 FADH2

    • 4 CO2

    • 2 ATP

    Cellular Respiration – Chapter 9


    Cellular respiration

    Cellular Respiration – Chapter 9 these are produced (2 turns of the Kreb’s Cycle):


    Electron transport chain
    Electron Transport Chain: these are produced (2 turns of the Kreb’s Cycle):

    • The second stage of aerobic or cellular respiration

    • Electron transport chain lines the inner membrane of the mitochondria

    Cellular Respiration – Chapter 9


    What happens in the electron transport chain
    What happens in the Electron Transport Chain: these are produced (2 turns of the Kreb’s Cycle):

    • NADH and FADH2 supply electrons and protons to the electron transport chain

    • The electrons move down the chain from molecules to molecule in a series of reactions

    • The protons are pumped outside the mitochondria

    Cellular Respiration – Chapter 9


    Electron transport chain cont
    Electron Transport Chain Cont. these are produced (2 turns of the Kreb’s Cycle):

    • As the protons return to the mitochondria matrix through ATP synthase, they release energy, that energy is used to make ATP

    • The electrons and protons are joined with oxygen this reaction makes ATP

    Cellular Respiration – Chapter 9


    Energy yield for aerobic respiration
    Energy Yield for Aerobic Respiration: these are produced (2 turns of the Kreb’s Cycle):

    • Efficiency of Aerobic Respiration = Energy used to make ATP

      Energy released by oxidation of glucose

    • Aerobic Respiration is 66% efficient (20 x more than glycolysis)

    • 1 molecule of glucose can produce up to 38 ATP in cellular respiration (see diagram) usually 36 ATP net yeild

    Cellular Respiration – Chapter 9


    Cellular respiration

    Cellular Respiration – Chapter 9 these are produced (2 turns of the Kreb’s Cycle):


    Cellular respiration

    Cellular Respiration – Chapter 9 these are produced (2 turns of the Kreb’s Cycle):


    Cellular respiration

    Cellular Respiration – Chapter 9 these are produced (2 turns of the Kreb’s Cycle):


    Cellular respiration

    Cellular Respiration – Chapter 9 these are produced (2 turns of the Kreb’s Cycle):