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Cellular Respiration

Cellular Respiration. Cellular Respiration. Includes the catabolic pathways that break down energy-rich compounds to produce ATP Aerobic Respiration refers to those pathways that require oxygen. Summary Reaction.

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Cellular Respiration

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  1. Cellular Respiration

  2. Cellular Respiration Includes the catabolic pathways that break down energy-rich compounds to produce ATP Aerobic Respiration refers to those pathways that require oxygen

  3. Summary Reaction Summarizes more than two dozen reactions that take place in different parts of the cell. C6H12O6 + O2  CO2 + H2O + ATP

  4. What types of organisms do cellular respiration?

  5. Where does cellular respiration take place?

  6. Where the magic happens  Intermembrane Space

  7. Stages and Locations • Glycolysis • Occurs in the cytoplasm • Pyruvate Oxidation • Occurs in mitochondrial matrix

  8. Stages and Locations • Krebs Cycle • Citric Acid Cycle (CAC) • Tricarboxylic Acid Cycle (TCA) • Occurs in mitochondrial matrix

  9. Stages and Locations • Electron Transport Chainand Chemiosmosis • oxidative phosphorylation • Occurs in the inner mitochondrial membrane

  10. 2 Important Players in CR... NADH FADH2

  11. NADH nicotinamide adenine dinucleotide Carries a lot of energy in its bonds Is produced all throughout CR

  12. NADH At the ETC, NADH loses its electrons (oxidized) NADH NAD+ + H+ These donated e- drive ATP synthesis

  13. NADH • For every NADH that is oxidized at the ETC, 3 ATP’s are made.

  14. FADH2(flavin adenine dinucleotide) • Carries energy in its bonds • Produced at Krebs cycle • Oxidized at the ETC to produce ATP FADH2 FAD + 2H+

  15. FADH2 • Only 2 ATP are produced for each FADH2 in the ETC

  16. So why is it so important to make ATP?

  17. ATP Adenosine triphosphate Carries a large amount of energy in its bonds ATP is used by all cells to run cellular processes

  18. ATP To release its energy ATP loses a phosphate group ATP ADP + Pi energy To make ATP: ADP + Pi ATP

  19. 2 Ways to make ATP...

  20. Substrate-level Phosphorylation ATP is formed directly in an enzyme-catalyzed reaction A phosphate group is removed from a substrate molecule and combined with ADP forming ATP

  21. Substrate level Phosphorylation

  22. Oxidative Phosphorylation • ATP is formed indirectly • Involves a # of sequential redoxrxns – with oxygen being the final e- acceptor • More complex than substrate level phosphorylation, but yields more ATP

  23. Oxidative Phosphorylation

  24. Overview

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