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MALARIA

MALARIA. PLASMODIUM VIVAX PLASMODIUM FALCIPARUM PLASMODIUM OVALE PLASMODIUM MALARIAE Dr.Rita Swaminathan Mr.Narayana Kamath. LIFE CYCLE. ALTERATION OF GENERATIONS asexual cycle (schizogony) sexual cycle (sporogony) ALTERATION OF HOSTS

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MALARIA

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  1. MALARIA PLASMODIUM VIVAX PLASMODIUM FALCIPARUM PLASMODIUM OVALE PLASMODIUM MALARIAE Dr.Rita Swaminathan Mr.Narayana Kamath

  2. LIFE CYCLE • ALTERATION OF GENERATIONS asexual cycle (schizogony) sexual cycle (sporogony) • ALTERATION OF HOSTS intermediate host (man) schizogony definitive host (mosquito) sporogony

  3. Life cycle

  4. Morphology-thin blood smear nucleus ring cytoplasm

  5. Morphology-thick blood smear ring

  6. Morphology Male gametocyte Female gametocyte

  7. Pathogenesis and Clinical features • Pre-patent period, & incubation period • Febrile paroxysms(Erythrocytic schizogony) • Hot stage , cold stage & sweating stage • Anaemia • Splenomegaly • Complications of P.falciparum

  8. Laboratory diagnosis • Peripheral smear : Thick smear,Thin smear • CBC • Flourescent microscopy(QBC) • Rapid tests :Malaria Ag detection test • DNA probes • Seroloical tests(ELISA)

  9. Treatment & prevention • Chemotherypy: Antimalarial agents • Antimosquito measures • Early diagnosis and radical cure for relapses • Malarial vaccine

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