Carbon
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Presentation Transcript
Isomer Examples • You Tube Video of Optical Isomerism
Contrast Caraway and SpearmintISOMERS • (get taste samples)
Thalidomide Isomers Treated nausea of women in 1950’s Changed to isomer form in the body that caused a birth defect
ISOMERS • L-dopa (Precursors to the neuro- transmitter dopamine) to treat Parkinson’s –but D-dopa causes (“D” polarize light to R.) deficiency of white blood cells • Allegra is the isomer of Seldane (for nose congestion) • Lexapro is the active isomer • of Celexa (antidepressants)
COMMON ELEMENTS OF MACROMOLECULES • CHNOPS • Carbon – hydrogen- nitrogen-oxygen-phosphorus-sulfur
FUNCTIONAL GROUPS: know them • Group of atoms attached to a carbon skeleton involved in chemical reactions • Five groups are polar, hydrophilic (water-loving) and are soluble in water • The sixth group, the methyl group, is nonpolar, and nonreactive
ADD: sulfhydryl group -SH
FUNCTIONAL GROUP:HYDROXYL GROUP • -OH • Organic compounds containing –OH groups are called alcohols • C2H5OH ethanol (or ethyl alcohol): molecular formula and • structural formula
FUNCTIONAL GROUP:CARBONYL GROUP • -C=O • If at the end, the compound is called an aldehyde (like acetaldehyde in ripe fruit). • If in the middle, it is called a ketone (broken down in liver, used in brain) • Commonly in sugars.
FUNCTIONAL GROUP:CARBOXYL GROUP • -COOH or • H acts as an acid (carboxylic acid) to donate H+ • EX: acetic acid CH3COOH
FUNCTIONAL GROUP:AMINO GROUP • -NH2 • Acts as a base by picking up a H+ (to make NH3) • Compounds with amino groups are called amines • EX: amino acids are building blocks of protein
FUNCTIONAL GROUP:PHOSPHATE GROUP • -OPO3-2 • Compounds with phosphates are called organic phosphates • Involved in energy transfer, ATP
FUNCTIONAL GROUP:METHYL GROUP • -CH3 • Compounds with methyl groups are called methylated compounds • EX: Found in DNA
ADD THIS FUNCTIONAL GROUP: Sulfhydryl group • –C–SH or R–SH • (S takes the place of O in a –OH group) (less polar) • -SH group can also be referred to as athiol group FYI: Smell like garlic, put in natural gas for an odor Methanethiol Cysteine
PRESENTATION: FUNCTIONAL GROUP - 7points • A. functional group • B. name compound it forms • C. depict the structural formula • D. show how to remember it • E. Creative • F. Easy for classmates to remember You tube • G. polar or nonpolar • EXTRA CREDIT: if you make a visual of your functional group for class display
WILL DO WORKSHEET • “Identifying Functional Groups” • Work hard like Larry here.
4 Types of Macromolecules • Proteins • Nucleic Acids • Carbohydrates • Lipids
Macromoleculeor Polymer • a large molecule consisting of many identical or similar subunits strung together
Polymer • A large molecule (macromolecule) consisting of many smaller molecules (monomers) into chains
Monomers • the subunits that serve as the building blocks
Polymerization • Joining monomers to make a polymer • LINK Animation of a Condensation Polymerization
Dehydration SynthesisA.K.A. polymerization Dehydration Synthesis You Tube
Dehydration Synthesis • Start with small molecules (monomers), by removing water end with large molecules (polymers)
Dehydration Synthesis • Monomers (small molecules) are linked together by a process that takes out a molecule of water to form a polymer (macromolecule).
Hydrolysis • Polymers are disassembled to monomers by hydrolysis in which bonds are broken by the addition of water
Hydrolysis • Start with large molecules (polymer) add water and end with small molecules (monomer)
Videos • You Tube Dehydration Synthesis and Hydrolysis • Easy animations • Making and Breaking
MACROMOLECULES • Receive chart of macromolecules and tips • Carbohydrates • Lipids • Proteins • Nucleic Acids
Carbohydrates are Made Of: • C : H : O or CH2O 1 : 2 : 1 EX: C6H12O6 glucose- most common monosaccharide C12H22O11 = 2 C6H12O6 −H2O
What functional groups are in carbohydrates? Carbonyl aldehyde or ketone Hydroxyl
Carbohydrates • “Sugars” • Names for Carbohydrates end in –ose • Monomers: monosaccharides
Structural formula Why would you choose one model over another? Abbreviated structure Space-filling model
Monomer of Carbohydrates:Monosaccharides • Simple sugar • -main use in body: fuel • EX: glucose – most common galactose –milk sugar fructose – fruit sugar