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Exploring Laxatives: Mechanisms and Uses

Dive into the world of laxatives and their mechanisms of action. Learn about different categories of laxatives and their uses in various industries. Understand the identification process and chemical constituents of Isphagula seeds. Discover the geographical distribution and morphological characteristics of this beneficial plant. This seminar, presented by Maharudra S. Rakh, covers essential information on laxatives for first-year pharmacognosy students.

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Exploring Laxatives: Mechanisms and Uses

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  1. WELCOME rmspharma@gmail.com @maharudra rakh

  2. A SEMINAR ON “Laxatives” Presented by MAHARUDRA S. RAKH M. PHARM ., M.B.A E- mail: rmspharma@gmail.com PHARMACOGNOSY First year

  3. Laxatives • Latin: Laxare:- means to -loosen • Laxatives are the drugs which loose the bowels (intestine) • Depending upon the intensities of drug effects they are categorized as follows- • Laxatives: suggest the elimination of soft formed stools (mild purgatives) ex. Senna, isapgol, liquid paraffin • Purgatives: suggest more fluid evaluation ex. Castor oil, aloe, rhubarb, cascara • Drastics: act intensely by irritating the mucous membrane of intestine ex. Jalap, podophyllum, colocynth • Hydrogogues: produce fluid motions ex. croton oil, colocynth • The mechanism of action of laxatives may be either bulk forming, irritant or emolllient depending upon the chemical nature of active constituent. rmspharma@gmail.com @maharudra rakh

  4. rmspharma@gmail.com @maharudrarakh

  5. Identification • mixes with half its volume of light petroleum ether (40 - 60°) • soluble in alcohol and insoluble in mineral oil • Uses • cathartic, lubrication, soap and textile industry, • in preparation of paints, enamel, varnishes, grease, polishes, printing ink, spirit • in preparation of ointments, creams and polishes rmspharma@gmail.com @maharudrarakh

  6. rmspharma@gmail.com @maharudrarakh

  7. rmspharma@gmail.com @maharudrarakh

  8. ISPAGHULA Synonyms: isapgol, isabgol Biological source: It consists of dried seeds of the plant known as Plantogo ovata Forskal belonging to family Plantaginaceae. Geographical distribution: In india mainly in gujarat, punjab, south rajasthan. Morphological characteristics: Colour: pinkish-grey or brown Odour: none Taste: mucilaginous, bland Shape: ovate like Size: 10-35mm length and 1 to 1.75mm in width rmspharma@gmail.com @maharudra rakh

  9. Chemical constituents: Contain mucilage, pentosan, sldobionic acid, rhamnose, fixed oil, and proteins Uses: Demulcent, laxative, emollinent, dysentery, in prep tablets and as stabilizer in icecream industry, in rheumatic pains rmspharma@gmail.com @maharudra rakh

  10. rmspharma@gmail.com @maharudra rakh

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