1 / 11

PANDAS

PANDAS. Sven Wiklund Barnneurolog Barnkliniken KRYH. Systematic clinical evaluation of children with Sydenham’s chorea suggested that specific clinical characteristics might define a homogeneous subgroup of patients with OCD and tic disorders, including Tourette’s disorder.

urvi
Download Presentation

PANDAS

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PANDAS Sven Wiklund Barnneurolog Barnkliniken KRYH

  2. Systematic clinical evaluation of children with Sydenham’s chorea suggested that specific clinical characteristics might define a homogeneous subgroup of patients with OCD and tic disorders, including Tourette’s disorder. • Presence of a tic and/or OCD disorder. • Pediatric onset. • Episodic course of symptom severity. • Association with GAHS infection. • Association with neurological abnormalities.

  3. 184 träffar i PubMed

  4. Fem kriterier, enligt Archelos och Hartung, för att faställa ett samband mellan antikroppar och neurologisk sjukdom • Identifierade antikroppar11 studier talar för en koppling och 10 studier emot. • Autoantikroppar identifierade i CNS hos människa.0 studier. • Autoantigen inducerar symtom hos försöksdjur.1 studie, som talar för. • Autoantkroppar inducerar symtom hos försöksdjur2 studier talar för och 1 emot. • Postitivt svar på immunmodulerande behandling1 RCT3 case studies med sammanlagt 6 patienter

  5. What is the mechanism behind this phenomenon? At present, it is unknown

  6. The children usually have dramatic, "overnight" onset of symptoms, including motor or vocal tics, obsessions, and/or compulsions.

  7. Is there a test for PANDAS? No. The diagnosis of PANDAS is a clinical diagnosis, which means that there are no lab tests that can diagnose PANDAS

  8. The treatments for children with PANDAS are the same as if they had other types of OCD or tic disorders. Children with OCD, regardless of whether or not their illness is strep triggered, benefit from cognitive behavioral therapy and/or anti-obsessional medications. At this time, however, there isn't enough evidence to recommend the long-term use of antibiotics.

More Related