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L.E.S. Definici?n. Enfermedad sist?micaSucesivas exacerbaciones y remisionesPresencia de m?ltiples autoanticuerposAnticuerpos antinucleares (AAN)Inflamaci?n en diversos ?rganos con dep?sitos de complejos inmunes. El compromiso del aparato locomotor y de la piel es muy com?nPuede haber manifes

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