1 / 10

European Journal of Clinical Nutrition 2011; 65:386-393. Brooke Beasley and Ruth Sullivan

Differential Effects of Walnuts vs Almonds on Improving Metabolic and Endocrine Parameters in PCOS . European Journal of Clinical Nutrition 2011; 65:386-393. Brooke Beasley and Ruth Sullivan. Polycystic Ovary Syndrome. Signs and Symptoms Menstrual irregularities Infertility

tea
Download Presentation

European Journal of Clinical Nutrition 2011; 65:386-393. Brooke Beasley and Ruth Sullivan

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Differential Effects of Walnuts vs Almonds on Improving Metabolic and Endocrine Parameters in PCOS European Journal of Clinical Nutrition 2011; 65:386-393. Brooke Beasley and Ruth Sullivan

  2. Polycystic Ovary Syndrome • Signs and Symptoms • Menstrual irregularities • Infertility • Masculinizing hormones - acne and hirsutism • Fluid-filled ovarian cysts • Metabolic Syndrome • Insulin resistance • Dyslipidemia • Increased inflammation

  3. Study Objective & Methods • Compare the impact of • MUFA in almonds to • PUFA in Walnuts • On metabolic and endocrine components of PCOS • Randomized prospective study • 31 women participated • Individual packets of nuts containing 31 g of fat • 46 grams almonds • 36 grams walnuts daily • 6 weeks

  4. Data Collected • Anthropometric • Weight • Height • Sugar • Insulin • OGTT • HgbA1C • Dyslipedemia • Total Cholesterol • HDL • TG • Leptin • Adiponectin • Inflammatory Markers • CRP • TNF • IL • Masculinizing Hormones • Total testosterone • Sex hormone binding globulin (SHBG) • Free Androgen Index (FAI)

  5. Significant Findings • Walnuts reduced HgbA1C levels • PUFAs stimulated insulin secretion • Both walnuts and almonds increased adiponectin • helps control insulin sensitivity • Both decreased circulating androgen levels • Walnuts increased SHBG • Almonds decreased FAI

  6. Strengths and Weaknesses • Strength • Well controlled re: compliance of nut intake • Collected unused portions • Weakness • Small sample size: 31 individuals • No control group with PCOS without nuts

  7. Database Research on PCOS The Natural Standard database: • PCOS Treatment: • Promote normal weight status • High intake of fruits, vegetables, whole grains • No estrogen-rich food sources (tomatoes, nonorganic red meat/dairy) • Low carb • High carb weight gain estrogen stored in fat cells • High estrogen promotes ovarian cysts *No reference regarding fat quantity/quality http://www.naturalstandard.com/databases/conditions/condition-pcos.asp

  8. Database Research on Metabolic Syndrome The Natural Standard Database News, December 2008: “Eating a Mediterranean diet rich in nuts may help reverse Metabolic Syndrome.” http://www.naturalstandard.com/news/news200812017.asp

  9. Our Treatment Strategy for PCOS Promote optimal body weight Low glycemic/anti-inflammatory diet Organic animal proteins MUFA and n-3 PUFA rich food sources (nuts) Liver support (cruciferous vegetables) Decrease phytoestrogens (soy) & caffeine Spearmint tea for hirsutism Reduce stress/toxic environmental exposure

  10. In Conclusion A general anti-inflammatory or Mediterranean diet including MUFA and PUFA rich almonds and walnuts appears to be helpful in managing metabolic and endocrine symptoms in PCOS.

More Related