CANTERBURY / WESTLAND ABSTRACT
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CANTERBURY / WESTLAND ABSTRACT This case follows the Radiation Treatment Planning process for a recurrent GlioblastomaMultiforme Brain patient. This patient received two courses of RT to the same site resulting in a total dose of 100Gy to the brain. Interesting points to be covered include patient history, RO prescription choice and associated evidence, planning process and patient implications. This case study will be focused on planning rather than treatment. Sat 31stAug 2013 Session 3/ CR2-4 13:51 – 13:55 HEAPHY 1 & 2 CASE RACE 2 – RT Jemma HURLEY
Jemma Hurley Radiation Therapist Canterbury District Health Board Case Race100gy Brain
Patient Information • 58 year old Female • Diagnosis: GlioblastomaMultiforme • Site: Left Brain
Patient History • May 2011: Surgical debulking GBM • June 2011: Commenced Radiation Therapy concurrent w Temozolomide • July 2011: Completed RT • Jan 2012: Completed 6th cycle Temozolomide • Nov 2012: Recurrent dysphagia & headaches • Dec 2012: Debulking recurrent GBM • commenced PCV chemo • March 2013: MRI progression • May 2013: Commenced Course 2 Radiation Therapy
Prescription • Course 1: 60Gy/30# to Left Brain • Course 2: 40Gy/20# to Left Brain • Total Dose to Left Brain = 100Gy
Volumes • Location of tumour made 100Gy possible • Screen dump
Patient Implications • Brain Necrosis • Only significant after 100Gy • Brain can recover • Benefit versus Risk • Survival • Further 5 months
References • Short SC. Re-irradiation of brain tumours – evidence, indications and limitations. European journal of cancer. 2009.