'Globin' presentation slideshows

The Thalassaemia Syndromes

The Thalassaemia Syndromes. Ahmad Sh. Silmi Msc Haematology, FIBMS. The Thalassaemia Syndromes. The thalassaemia are heterogeneous group of inherited disorders, which are characterized by reduced or absent synthesis of one or more globin chain type.

1.59k views • 128 slides

Hematology

Hematology. Anemia. deficiency of red blood cells and/or hemoglobin reduced ability of blood to transfer oxygen to the tissues, and this causes hypoxia. Three main classes excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss

1.6k views • 116 slides

Protein Function: Oxygen Binding Proteins

932 views • 73 slides

Diagnostic Hematology: Disorders of Hemoglobin and Gammopathies

Diagnostic Hematology: Disorders of Hemoglobin and Gammopathies. Muhammad Shoaib Khan GM Centre - 1. a globin. b globin. b globin. a globin. Hemoglobin structure. Hgb A tetramer. Development period. a cluster - chromosome 16. Globin chain component. % of adult Hgb.

850 views • 66 slides

HEMOGLOBINOPATHIES: Thalassemia and Sickle Cell (with brief mention of a few others)

HEMOGLOBINOPATHIES: Thalassemia and Sickle Cell (with brief mention of a few others). Peter Newburger, MD Departments of Pediatrics and Cancer Biology. Epidemiology and the malaria hypothesis.

1.62k views • 56 slides

Chapter 19

Chapter 19. Cardiovascular System: The Blood. Cardiovascular System: The Blood. Functions of the Blood Plasma Formed Elements Hemostasis Blood Grouping Diagnostic Blood Tests. Cardiovascular System. Fig. 1.3 pg 8.

702 views • 50 slides

1.67k views • 49 slides

Introduction to Blood, Erythrocytes and Anemia

Introduction to Blood, Erythrocytes and Anemia. Clinical Pathology Ms. Canga. Introduction to Blood, RBCs, and Anemia Topics for discussion:. Function of blood and various components Composition Fluid Cellular (Specific to erythrocytes) Anemia Staining. The Function of Blood.

692 views • 45 slides

Structures of Myoglobin and Hemoglobin

Structures of Myoglobin and Hemoglobin. Myoglobin ( Mb ) - monomeric protein that facilitates the diffusion of oxygen in vertebrates Hemoglobin ( Hb ) - tetrameric protein that carries oxygen in the blood

2.44k views • 33 slides

Structures of Myoglobin and Hemoglobin

Structures of Myoglobin and Hemoglobin. Myoglobin ( Mb ) - monomeric protein that facilitates the diffusion of oxygen in vertebrates Hemoglobin ( Hb ) - tetrameric protein that carries oxygen in the blood

777 views • 33 slides

Blood

Blood. Week 6 Dr. Walid Daoud, A. Professor. Blood ____________________________. Blood is a part of extracellular fluid and composed of 2 parts: 1- Fluid part or Plasma (55%). 2- Cellular part (45%): . Red blood corpuscles (erythrocytes). . White blood cells (leukocytes).

524 views • 28 slides

Hemoglobin Structure & Function

Hemoglobin Structure & Function. Objectives of the Lecture. 1- Understanding the main structural & functional details of hemoglobin as one of the hemoproteins . 2- Identify types & relative concentrations of normal adult hemoglobin with reference to HBA1c with its clinical application.

1.78k views • 27 slides

HEMOGLOBIN

HEMOGLOBIN. Heme molecule. Fe. HAEMOGLOBIN. INTRODUCTION STRUCTURE TYPES SYNTHESIS FATE DERIVATIVES CLINICAL- ANAEMIAS - HAEMOGLOBINOPATHIES - PORPHYRIAS. Pigment present inside RBCs Carries O 2 and CO 2

907 views • 26 slides

Gas Transport in the Blood

Gas Transport in the Blood. Dr Shihab Khogali Ninewells Hospital & Medical School, University of Dundee. What is This Lecture About?. Understand the effect of partial pressure on O 2 and CO 2 carriage in the blood Understand the means of O 2 carriage in the blood

522 views • 23 slides

The Thalassemias

A one year old boy was brought by his mother in Child OPD MH with h/o Pallor, inability to feed and lethargy O/E boy is markedly pallor TLC : 7.8x109/l Hb : 5 g/dl Plt : 290x109/l Numerous circulating normoblasts seen.

395 views • 23 slides

??? ???? ?????? ??????

??? ???? ?????? ??????. ANEMIA Dr Mokarian ICM 83/2/7. Dr mokarian. PROPERTIES OF THE HUMAN HEMOGLOBINS. HEMOGLOBIN STRUCTURE: 1- a tetramer of globin polypeptide chains A pair of a-like chains 141 amino acids long A pair of b-like chains 146 amino acids long HbA( a2b2)

346 views • 21 slides

Hemoglobin Electrophoresis

Hemoglobin Electrophoresis. Practical Clinical Hematology. 6. Electrophoresis.

1.58k views • 20 slides

TRANSPORT OF RESPIRATORY GASES

TRANSPORT OF RESPIRATORY GASES. RESPIRATORY GASES; How are they transported in the blood???. CARBONDIOXIDE, CO 2. OXYGEN, O 2. The only way for Oxygen to be carried around the body is by the HEAMOGLOBIN, in red blood cells. Carbondioxide is transported by

692 views • 17 slides

Approaches to Sequence Analysis

Approaches to Sequence Analysis. Data {GTCAT,GTTGGT,GTCA,CTCA}. Parsimony, similarity, optimisation. TKF91 - The combined substitution/indel process. Acceleration of Basic Algorithm Many Sequence Algorithm MCMC Approaches. GT-CAT GTTGGT GT-CA- CT-CA-. Ideal Practice: 1 phase analysis.

257 views • 16 slides

Sources of Amino Acids

Sources of Amino Acids. De Novo Synthesis CO 2 fixation (ala, asp, glu) little incorporated into protein Host Plasma ? uptake of all amino acids in vitro growth requires ile, met, cys, gln, glu Digestion of Host Hemoglobin. Hemoglobin. 95% of total erythrocyte protein

261 views • 16 slides