Chapter 21. Drugs for Parkinson’s Disease. Parkinson’s Disease. Parkinson’s disease (PD) is a neurodegenerative disorder of the extrapyramidal system associated with disruption of neurotransmission in the striatum Characterized by dyskinesias and akinesia
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Drugs for Parkinson’s Disease
Fig. 21-1. A model of neurotransmission in the healthy striatum and parkinsonian striatum.
Fig. 21-2. Steps leading to alteration of CNS function by levodopa.
Fig. 21-3. Conversion of levodopa to dopamine.
Fig. 21-4. Fate of levodopa in the presence and absence of carbidopa.