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Membranes. Continuous sheets of cell aggregations that form barrier layer(s)Comprised of epithelial
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1. Membranes & Integument Chapter 3 & 4
2. Membranes Continuous sheets of cell aggregations that form barrier layer(s)
Comprised of epithelial & connective tissue
Function-
Barriers- basement membrane
Cover, line & protect
May provide moisture
3. Membrane Types Serous membrane
Mucous membrane
Synovial membrane
Cutaneous membrane
4. Serous Membrane Line sealed internal division of ventral body cavities
Structure
Simple squamous epithelium
Areolar connective tissue
Location- line cavities & organs
2 components
Parietal & visceral
Function-
reduces friction
Provides moisture- Transudate
Serous membrane examples
Pleura
Peritoneum
Pericardium
endothelium
5. Endothelium
6. Mucous Membranes Aka mucosa
Structure
Simple or stratified epithelia
Areolar connective tissue
Functions- protective barrier
Epithelia moist with secretions
Mucus, urine, semen, saliva
Absorb, secrete, protect
Locations-Line cavities that communicate with the exterior
Digestive- simple columnar
Respiratory- pseudostratified
Mouth- stratified squamous
Urinary tract- transitional
7. Goblet Cell
8. Synovial Membrane Line joint cavities & line hyaline cartilage of bone ends
Structure-
Discontinuous simple squamous or cuboidal epithelium
Areolar connective tissue
Function- secrete synovial fluid
fibroblast
Lubricate & nourish joint cartilage
MAcrophage
Immune defends joint
Location- line & enclose moveable joints
Knee, elbow, shoulder, hips
9. Synovial Membrane
10. Cutaneous Membrane Function- protection
Dry membrane
Location- covers body surface
Majority of skin but NOT all
Structure
Stratified squamous epithelium- epidermis
Loose areolar CT Proper- dermis
Dense CT Proper- dermis
11. Integumentary System Largest organ- 18 sq ft
14% of body weight
Aka Integument
Organ system
Forms continuous sheet of cells covering the bodies surface
Contains all 4 primary tissues
2 components
Cutaneous membrane
Epidermis, dermis, (hypodermis)
Accessory structures
Hair, nails, glands
14. Integument Functions Protection
Temperature maintenance
Nutrient synthesis & storage
Sensory reception
Excretion & secretion
15. Protection from Abrasion
16. Protection from Dehydration & Pathogens
17. Protection from Pathogens
18. Protection from UV
19. Melanin
21. Temperature Maintenance Vasoconstriction
Vasodialation
22. Nutrient Synthesis & Storage
23. Ricketts
24. Storage- Fat Mouse
25. Sensory Reception
26. Excretion & Secretion Human fingertip surface showing fingerprint ridges and sweat droplets
27. Epidermis Stratified Squamous Epithelium - multiple layers with multiple cell types
Protective
Keratinized
Avascular
High regeneration
rate
28. Epidermis Cells Keratinocytes
Keratin
Melanocytes- melanin
Merkel’s cells- reception
Langerhan’s cells- immune
Protein fibers- strength & flexibility
29. Keratinocytes Primary cell of epidermis- 90%
Contain lots of keratin
Horn
Hydrophobic
Abrasion & dessication protection
30. Melanocytes Relatively small component of epidermis- 6%
Protects against UV
Melanin- light absorption pigment
Stimulated by UV exposure
31. Melanoma
32. Langerhans Cells 3-8%
Immune function
Assists immune function
33. Merkel Cells Less than 2%
Specialized sensory cells
Pressure & touch
Increase sensitivity in
areas lacking hair (glabrous skin)
34. Merkel Cells
35. Epidermis Layers Aka strata
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum germinativum
(aka Basale)
37. Stratum Corneum Corneum= “horny”
Dry, water resistant
Primarily keratinocytes
Enucleate
Dead cells
Thickness varies on
abrasion
Few- 30 layers
39. Stratum Lucidum Lucidus = clear
Only visible in thick skin
3-5 layers of keratinocytes
40. Thick Skin
41. Thin Skin
42. Stratum Granulosum Granulum= little grain
Keratohyalin granules
44. Stratum Spinosum Spina = prickly
Keratinocytes 8-10 layers
Contains Langerhans cells
46. Stratum Germinativum Aka basale
Germen = “sprout”
Deepest single layer of
germative cells
Adult stem cells
Pleuripotent- hair, gland, epi
Contains Melanocytes
Skin pigmentation
48. Basal Cell Carcinoma
50. Epidermis Et. Al.
51. Skin Mites
52. Epidermis Fauna
53. Dust Mites
54. dermis
55. dermis