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This supplemental figure shows a significant relationship between the numbers of MC1-positive and AT8-positive neurons in the cerebral cortex of a P301Lhtau-apoe wild type mouse. The micrograph inset displays a double-labeled section with MC1-IR (DAB stain) and AT8-IR (Alexa fluor). The scale bar is 100 µm.
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Supplemental Figure 1. The number of MC1-positive neurons is related to the number of AT8-positive neurons (***** p < 0.00001). Inset: micrograph of a double-labelled section of cerebral cortex from a P301Lhtau-apoe wild type mouse, MC1-IR (DAB stain), AT8-IR (Alexa fluor). Scale bar = 100 m