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Supplemental Figure 1. c. . MGC-803. 4. 4. 3. 3. miR-185 levels (fold). 40. TUNEL positive cells (\%). 2. 2. . 1. 1. 20. 0. 0. . 60. 60. 0. –. CDDP(30 m M). +. +. +. TUNEL positive cells (\%). 40. 40. . –. –. –. miR-185 AntagomiR. +. –. –. –.

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Presentation Transcript
slide1
Supplemental Figure 1

c

MGC-803

4

4

3

3

miR-185

levels (fold)

40

TUNEL positive

cells (%)

2

2

1

1

20

0

0

60

60

0

CDDP(30 mM)

+

+

+

TUNEL positive

cells (%)

40

40

miR-185 AntagomiR

+

AntagomiR control

4

+

20

20

3

miR-185

levels (fold)

0

0

2

DOX (2 mM)

+

+

+

+

+

+

f

1

+

+

miR-185 AntagomiR

+

+

AntagomiR control

0

MGC-803

+

miR-185

2

_

_

normal

+

b-gal

40

_

_

Cleaved Caspase-3

cancer

TUNEL positive

cells (%)

1.5

Actin

20

Relative miR-185 levels

DOX (2 mM)

+

+

+

1

miR-185 AntagomiR

0

+

+

miR-185

AntagomiR control

+

+

b-gal

0.5

+

+

+

CDDP (3 mM)

0

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

Patient Number

e

a

d

b

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