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Oracle Health Sciences Global Business Unit Strategy. Steve Rosenberg Senior Vice President and General Manager Oracle Health Sciences Global Business Unit. Clinical R&D - What hasn’t Changed…. Improved Outcomes & Care. Greater Safety. Reduced Costs. Streamlined R&D.

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oracle health sciences global business unit strategy

Oracle Health Sciences Global Business Unit Strategy

Steve Rosenberg

Senior Vice President and General Manager

Oracle Health Sciences Global Business Unit

clinical r d what hasn t changed
Clinical R&D - What hasn’t Changed…
  • Improved Outcomes & Care
  • Greater Safety
  • Reduced Costs
  • Streamlined R&D
clinical r d what continues to change
Clinical R&D - What Continues to Change …
  • Science & Technology
  • Clinical R&D Process
  • Patient Engagement
  • Clinical R&D Landscape
oracle health sciences
Oracle Health Sciences
  • Accelerate clinical development
  • Support entire drug safety lifecycle
  • Enable clinical data aggregation

Life Sciences

  • Power enterprise healthcare analytics
  • Enable provider/payer integration
  • Drive personalized medicine
  • Healthcare
  • The movement from clinical research to clinical care
  • Develop collaboration networks for providersand life sciences companies
  • Continuum
optimizing clinical research development
Optimizing Clinical Research & Development

Analytics and Insights

Planning & Budgeting

Trial Management

& Monitoring

Randomization & Trial Supply Management

Comprehensive Electronic Data Capture

Clinical Data Aggregation& Reporting

Signal Detection

Safety Lifecycle

HEALTH SCIENCES CLOUD

oracle life sciences
Oracle Life Sciences

Broadest, best-of-breed applications

Focus on integration

The highest standards of scalability, security, and privacy

recent oracle life sciences innovations
Recent Oracle Life Sciences Innovations

MOBILITYINFORM, CRA & ANALYTICS

KEY PRODUCT & THIRD PARTY INTEGRATIONS

CLINICAL MONITORING CLOUD

RISK BASED MONITORING

DATA MANAGEMENTWORKBENCH

REAL-WORLD SAFETY SURVEILLANCE

& COMPARATIVE EFFECTIVENESS

INFORM ADVANCED MOLECULAR ANALYTICS

MEDICATION ADHERENCE (PROTEUS)

slide10

Medication Adherence

  • FDA-approved ingestible sensors
  • Captures the body’s physiologic responses and behaviors
  • Sends digital health information to a mobile app
  • Oracle’s clinical trial applications customers have exclusive access to real-time data on therapeutic use

8

slide11

Medication Adherence

  • Medication compliance insight
  • Better dose selection
  • Fewer Phase III failures
  • Improved drug safety

9

slide12

DEEP-ROOTED COMMITMENT

TO DRIVING CLINICAL R&D PROCESS

OPTIMIZATION

AND ANALYTIC INSIGHTS

healthcare providers are facing
Healthcare Providers are Facing:

Changing business models and risk shifting

Margin pressure – cost, revenue, and volume

Immediate Focus:

  • Operational effectiveness
  • Risk-based revenue

Consolidation pressure

Aging population and management of chronic diseases

Evolves Over Time:

Increased complexity in regulation

  • Patient engagement and compliance
  • Care coordination
  • Population health
  • Precision medicine
powering enterprise healthcare analytics
Powering Enterprise Healthcare Analytics

Oracle

Enterprise Healthcare

Analytics

Enabling Value Through

Multiple & Disparate

Data Sources

Normalize

Aggregate

Analyze

  • Clinical
  • Finance
  • Human Resources
  • Supply Chain
  • Claims
  • Genomics
  • Research
  • Clinical Trials
  • 3rd Party Data

Client Developed Apps

Comprehensive Healthcare Data Model

Third Party Apps

Combines Clinical and OMICS Data

Oracle Apps

Data Governance

Productized Data Loaders

Application Choice

Leverages Oracle Technology

slide17

Harnessing Big Data for Life Sciences & Healthcare

Delivers:

Biomarker discovery

Protocol validation and patient recruitment

Patient stratification

Safety and comparative effectiveness

Population health

Precision medicine

  • Volume and availability of data continues to increase
  • Data will have various strengths and significance
  • Velocity of data is coming in faster than ever before
  • Who better than Oracle to attack this?

Genomics

Petabytes of information

Real-World Data

Variety of data sources

Sensors

Velocity of real-time data

slide18

Harnessing Big Data for Life Sciences & Healthcare

Delivers:

Biomarker discovery

Protocol validation and patient recruitment

Patient stratification

Safety and comparative effectiveness

Population health

Precision medicine

Genomics

Petabytes of information

Oracle Health Sciences

Real-World Data

Variety of data sources

Sensors

Velocity of real-time data

effectiveness of most drugs
Effectiveness of Most Drugs

Cost of Ineffectivenessto Healthcare System

Major Drug

Drug Effectiveness

Hypertension Drugs

ACE Inhibitors

10-30%

$390 million – $1.2 billion

Heart Failure Drugs Beta Blockers

15-25%

$345 million – $575 million

Anti Depressant Drugs

SSRIs

20-50%

$2.3 billion – $5.8 billion

Cholesterol Drugs Statins

30-70%

$3.8 billion – $8.8 billion

Asthma Drugs Beta-2-agonists

40-70%

$560 million – $1.0 billion

Source: The Personalized Medicine Coalition

slide20

Improving Population Health and Patient Outcomes

CURRENT

TRANSFORMATION

  • Targeted treatments
  • More effective trials
  • Faster time to market
  • Improved safety
  • Dramatically lower costs

Combining Clinical and OMICS data

cloud based collaborative r d
Cloud-Based Collaborative R&D

Oracle Health Sciences Network

Healthcare Provider

Participants

Life Sciences

Participants

  • While Ensuring:
  • Full control of de-identified data
  • Protection of Institutional IP
  • Respect for patient consent
  • Full HIPAA compliance

Network Participants Include:

why oracle health sciences
Why Oracle Health Sciences?

INDUSTRIAL STRENGTH CAPABILITY

BEST-OF-BREED TECHNOLOGY

UNMATCHED DOMAIN EXPERTISE

INNOVATION & TRANSFORMATION

DEEP & BROAD DATA MANAGEMENT

COMMITTED INVESTMENT IN LIFE SCIENCES & HEALTHCARE

slide23

FROM PIPELINE TO PATIENT

OPTIMIZINGAND TRANSFORMING

LIFE SCIENCES AND HEALTHCARE