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THE IMMUNE SYSTEM. The Invaders. The Defender. COMPONENTS OF THE IMMUNE SYSTEM. Cellular components of the immune system. Lymphocytes. Granulocytes. Others. Phagocytes. B-cell. Mononuclear phagocyte. Basophil. Platelets. T-cell. Neurtrophil. Mast cell. Large granular lymphocyte.

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Presentation Transcript
the immune system
THE IMMUNE SYSTEM

The Invaders

The Defender

components of the immune system
COMPONENTS OF THE IMMUNE SYSTEM

Cellular components of the immune system

Lymphocytes

Granulocytes

Others

Phagocytes

B-cell

Mononuclear phagocyte

Basophil

Platelets

T-cell

Neurtrophil

Mast cell

Large granular lymphocyte

Eosinophil

Antibodies

Cytokines

Complement

Inflammatory mediators

Soluble mediators of the immune system

origination of cellular components
ORIGINATION OF CELLULAR COMPONENTS

Lymphoid

stem cell

T-cell

B-cell

Plasma

cell

Natural

killer cell

Pluripotent Stem cell

Neutrophil

Monocyte

Eosinophil

Basophil

Mast cell

Platelets

Myeloid

Stem cell

Macrophage

the evolution of immunity
THE EVOLUTION OF IMMUNITY

Immunity

Non-specific

Immediate onset

Specific

Delay onset

Innate immunity

Acquiredimmunity

Humoral

Immune Response

Cellular

Immune Response

Antibodies production

T-cell activation

innate immunity
INNATE IMMUNITY

Pathogenic invasion

Bacteria

Viruses

1st Line Defense

Skin

Ciliatedcells

Lysozyme

Coughing

Vomitting

2nd Line Defense

Blood clot

Mast cell

Cytokines

Leukocytes

the inflammatory response
THE INFLAMMATORY RESPONSE

Tissue injury caused by pathogenic invasion

Increased

capillary

permeability

Capillary

widening

Leukocyte

attraction

Systemic

response

Increased

blood flow

Release

of fluid

Leukocytic

migration

Leukocytic

proliferation

Heat, Redness, Tenderness, Swelling, Pain

the complement cascade
THE COMPLEMENT CASCADE

Alternative

Classical

Antibody binding

Mannose binding

The Complement System

Opsonization

Inflammation

Cytolysis

acquired immunity
ACQUIRED IMMUNITY

Humoral Immunity

Cytokines

B-Cell Activation

Activated

TH cell

Antibodies Production

Cytokines

Cytotoxic T-Cell Activation

Cell lysis

Cell-mediated Immunity

attributes of acquired immunity
ATTRIBUTES OF ACQUIRED IMMUNITY

Immunological Specificity

Immunological Tolerance

Receptor

APC

Immunological memory

Activated T-cell

B-cell

Plasma

cell

Memory

B-cell

Mature

T-cell

Memory

T-cell