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International Workshop on  Pharmacogenomics and Pharmacogenetics:  Current Challenges and  Bioinformatics Support. Conclusions. PGx is a scientific discipline that offers interesting opportunities for improving health care and for carrying out exciting research. PGx approaches can save money:

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International Workshop on Pharmacogenomics and Pharmacogenetics: Current Challenges and Bioinformatics Support

Conclusions

  • PGx is a scientific discipline that offers interesting opportunities for improving health care and for carrying out exciting research.

  • PGx approaches can save money:

    • to the healthcare system

    • during the drug discovery and development processes (from target identification to patient recruitment in the clinical trials)

  • Cost-effectiveness studies on the introduction of PGx strategies should be carried out.

  • Inter-disciplinary approaches are required for PGx research including genetics, systems biology, medicinal chemistry, pharmacology, as well as clinical and computational sciences, among other disciplines.

  • Dialogue between pharmacogenomics and chemogenomics should increase.

  • Bioinformatics tools plays a key role in PGx research. It can benefit from integrated knowledge management and exploitation (“biomedical informatics” strategies).

  • Increased collaboration between all the stakeholders is advisable:

    • Regulatory authorities, industry and academia

    • Basic and clinical researchers

    • Experimental and computational scientists

    • At the local and international level

  • More educational activities on PGx are required. PGx training should be part of the MD, pharmacy and biology curricula.


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