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40 countries New sites added to regions since we began: CCASAnet – Mexico

40 countries New sites added to regions since we began: CCASAnet – Mexico West Africa – Nigeria Southern Africa – Zambia Asia – Vietnam. NA-ACCORD – When to start CCASAnet – Mortality; site assessments East Africa – LTFU Central Africa – Discordant couples; ETOH

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40 countries New sites added to regions since we began: CCASAnet – Mexico

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  1. 40 countries • New sites added to regions since we began: • CCASAnet – Mexico • West Africa – Nigeria • Southern Africa – Zambia • Asia – Vietnam

  2. NA-ACCORD – When to start • CCASAnet – Mortality; site assessments • East Africa – LTFU • Central Africa – Discordant couples; ETOH • Southern Africa – IRIS, Peds ART outcomes • West Africa – pediatric mortality on ART • Asia – ART and anemia (1st global concept); HBV & HCV impact on HIV outcomes

  3. ARRA* Initiatives IeDEA adds Malaria • Malaria surveillance at “Network Trial sites” with epidemiology led by IeDEA investigators • Collaboration with DMID • *American Recovery and Reinvestment Act of 2009

  4. NIH/PEPFAR Supplements • Implementation Science • Inform programs: efficiency, effectiveness • Impact evaluation • Limited Competition • Current grantees; no limit to # of applications • Research at PEPFAR funded sites (direct/indirect) • 5-page concepts • 1-year projects only (potential for carry forward x1 yr)

  5. IeDEA II (funding starts 2011) • Enhance analytical capacity - complex analysis • Manage impact of loss to follow-up • Selected enhancements of data: adverse events, mortality, risk behaviors • Strengthen links to other programs: Cancer, TB, PMTCT, Pediatric to Adult • Expand to cover the “Big 3 +” (HIV, Malaria, TB, hepatitis)

  6. IeDEA RFA what is knowable(today that is) Dates to keep in mind • Published mid July 2010 • Due mid November 2010 • Reviewed winter 2010/2011 • Awarded spring/summer 2011 Funding • Slightly more money overall • Same institutes (at least) NIAID, NCI, NICHD New Format

  7. RESTRUCTURED RESEARCH PLAN Old Application New Application

  8. Other Sections Personal Statement:Tell us why your experience and qualifications make you particularly well-suited for your role in the project Publications: Will be encouraged to include no more than 15 using recency, importance to the field, and/or relevancy to the application Total Biosketch will still be limited to 4 pages, including the education table at the top Environment -Address how the scientific environment will contribute to probability of success of the project, unique features of the environment, etc. For ESIs, provide a description of the institutional investment in the success of the investigator.

  9. http://odoerdb2.od.nih.gov/PeerReview/Revised_Page_Limits.pdfhttp://odoerdb2.od.nih.gov/PeerReview/Revised_Page_Limits.pdf

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