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Asthma - PowerPoint PPT Presentation


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Asthma. By: Emily Ngo. Asthma Background. Asthma is a chronic disease that affects up to 150 million people in the world Asthma is an inflammatory disease in the lungs that causes constriction in the airways Like many other diseases, asthma can be controlled but not cured.

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Presentation Transcript
asthma

Asthma

By: Emily Ngo

asthma background
Asthma Background
  • Asthma is a chronic disease that affects up to 150 million people in the world
  • Asthma is an inflammatory disease in the lungs that causes constriction in the airways
  • Like many other diseases, asthma can be controlled but not cured
asthma background cont d
Asthma background cont’d…
  • Many cells contribute to the inflammation
  • The inflammation causes wheezing, coughing, chest tightness, and breathlessness
cells that cause inflammation
Cells that cause inflammation

lymphocyte

eosinophil

mast cell

epithelial cell

fibroblast

macrophage

neutrophil

T-lymphocyte

t lymphocytes produce cytokines
T-lymphocytes produce cytokines…

Cellular Immunity

  • TH1: IL-2, INF-γ

Allergic Inflammation

  • TH2: IL-4, IL-5, IL-10, IL-13

*What if there is a balance/imbalance of TH1/TH2?

treatments
Treatments
  • Asthma Therapy:
    • Environmental Controls
    • Immunotherapy (Allergy Injections)
    • Symptomatic Control (bronchodilating agent)
    • Disease Modifiers (affect inflammation)
environmental control measures
Environmental Control Measures

Allergen Avoidance

  • House Dust mites
  • Grass Pollen
  • Indoor Pets
  • Feathers and Down