1 / 20

Calcium signaling in immunocytes

Calcium signaling in immunocytes.

varsha
Download Presentation

Calcium signaling in immunocytes

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Calcium signaling in immunocytes

  2. “The sensitivity of protoplasm and its response to stimulation are believed to be due to a sensitivity to free calcium ion and it is believed that the freeing of calcium and the reaction of this calcium with the protoplasm inside the cell is the most basic of all protoplasmic reactions”. Lewis Victor Heilbrunn, An Outline of General Physiology (1943)

  3. Randriamampita C. et al., Biol. of the Cell, 2004

  4. Braiman A. et al., EMBO J., 2006

  5. Feske S., Nat. Rev. Immunol., Sep. 2007

  6. Macian F., Nat. Rev. Immunol., Jun. 2005

  7. Lewis RS., Biochem. Soc. Transact., vol31(5), 2003

  8. Macian F., Nat. Rev. Immunol., Jun. 2005

  9. Feske S., Nat. Rev. Immunol., Sep. 2007

  10. Y Y PH EF X PH* SH2 SH2 SH3 PH* Y C2 775 783 Structure of PLCg1

  11. PLC-YFP Overlay LAT-CFP Braiman et al., EMBO J., 2006

  12. SH2N SH3 SH2C LAT PLC Gads Vav c-Cbl Grb2 Vav Slp76 Itk Braiman A. et al., EMBO J., 2006

  13. Feske S., Nat. Rev. Immunol., Sep. 2007

  14. Feske S., Nat. Rev. Immunol., Sep. 2007

  15. Winslow MM. et al, Curr. Opin Immunol.,vol.15, 2003

  16. Gwak Y. et al, Cell Calcium, 42, 2007

  17. Liou J. et al., Curr. Biol., 2005

  18. Feske S. et al., Nature, 2006

  19. Feske S. et al., Nature, 2006

  20. Liou J. et al., PNAS, 104(22), 2007

More Related