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Apheresis Red Cell Technology

Apheresis Red Cell Technology. Strategy for Increasing the Blood Supply. Units of Group O positive blood listed as available versus requested by Blood Centers . 20,000. 18,000. 16,000. 14,000. 12,000. 10,000. 8,000. 6,000. 4,000. 2,000. National Blood Exchange - Supply and Demand.

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Apheresis Red Cell Technology

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  1. Apheresis Red Cell Technology Strategy for Increasing the Blood Supply

  2. Units of Group O positive blood listed as available versus requested by Blood Centers 20,000 18,000 16,000 14,000 12,000 10,000 8,000 6,000 4,000 2,000 National Blood Exchange - Supply and Demand Units requested Units listed Winter Fall 25,000 20,000 15,000 Number of Units 10,000 5,000 1990-91 1994-95 1991-92 1992-93 1993-94 1995-96 1996-97 1997-98 1989-90 1989-90 1991-92 1992-93 1993-94 1994-95 1995-96 1996-97 1997-98 1990-91 Year Year Source: AABB News, March 1999

  3. U.S. Blood Donation DeclineNational Blood Data Resource Center • Blood Supply ,Transfusions  • By year 2000 the blood supply will  by 600,000 units. • This is 249,000 units < expected need • Blood supply trend: • Units Transfused1992 - 11.3 million transfusion1997 - 11.5 million transfusions • Units Collected • 1992 - 13.2 million donations • 1994 - 12.9 million donations • 1997 - 12.3 million donations

  4. Red Cell Apheresis Protocols • Two-Units of Red Cells • Red Blood Cells and Plasma • From 1 donation

  5. Apheresis Red Cell FDA Clearance History April 1998 First 2-RBC Blood Bank License 1997 510(k) clearance for Allogeneic 2-RBC 1996 510(k) clearance for Autologous 2-RBC 1995 510(k) clearance for Allogeneic / Autologous RBC & Plasma

  6. 2RBC Allogeneic Nomogram • Males • 130 pounds • 5’1” height • 40% hematocrit • 112 day deferral • Females • 150 pounds • 5’5” height • 40% hematocrit • 112 day deferral RBCP nomogram is the same as whole blood.

  7. Worldwide Apheresis Red Cell Growth * Actual data annualized.

  8. 2RBC Conversion Strategy: Group O & B Donors 962,000 more RBC Products (Early) (8%) 1,620,000 more RBC Products (Mature)(14%) Assumption: 12 Million WB Donations. 70% Mobile.

  9. Face-to-Face Conversion Success • Whole Blood to Apheresis Collection through face-to-face conversion. • No telerecruitment used • Approximately 50% increase in 2RBC procedures from April to June • Approximately 21% increase in RBCP procedures from April to June Procedures

  10. Apheresis Red Cell Leukoreduction • Europe in-line leukoreduction since 1996. • Domestic 2RBC in-line leukoreduction in clinical trials.

  11. Economics • Recently Haemonetics and an economics consulting firm collected data from 15 blood centers across the United States pertaining to whole blood collections. • Study conclusion of 15 Blood Centers: clear cut advantage in replacing certain whole blood collections.

  12. Conclusion Apheresis Red Cell Technology

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