From Discoveries to Cures

1. SOM Graduate Education Office Paul MacDonald Martin Snider Robert Petersen Monica Montano George Dubyak Diana Ramirez-Bergeron Joseph Williams Deborah Noureddine MalanaBey Dan Korgan From Discoveries to Cures

2. Seeds of Discovery The Ph.D. White Lab Coat Ceremony 76 students entering 11 different programs 57 % female, 43 % male 11 different countries (33 %) 36 % from Ohio, 11 % from CWRU From Discoveries to Cures

3. Guiding Principles for Graduate Education preparing students for success as future leaders in the rapidly changing biomedical research environment of the 21st century. • an interdisciplinary, concept-driven curriculum rather than content-driven • approaches that stimulate active interchange of ideas among students and faculty • fosters collaboration among students and faculty…safe learning environments • students and faculty as colleagues • independent study, self-directed learning, and life-long learning skills • a professional skill set beyond the academic research profession From Discoveries to Cures

4. Guiding Principles for Graduate Education preparing students for success as future leaders in the rapidly changing biomedical research environment of the 21st century. • Students develop a set of core research competencies: • Broad foundational knowledge of discipline, • depth of knowledge in their field • Interdisciplinary knowledge of experimental methods • Think and communicate clearly, oral and written • Plan and execute experiments • Read, critically evaluate, and integrate scientific literature • Ability to think creatively and acquire creative problem solving skills From Discoveries to Cures

5. Ph.D. Graduate Programs at CWRU Biochemistry Tracks: RNA Biology Structural Biology & Biophysics Bioethics Biomedical Engineering Cell Biology Epidemiology and Biostatistics Genetics Tracks: Developmental Biology Molecular Biology and Microbiology Molecular Medicine Molecular Virology Neurosciences Tracks: Developmental Biology Nutrition Pathology Tracks: Cancer Biology Exp. Pathology Immunology Mol. Cell. Basis of Disease Pharmacology Tracks:CancerTherapeutics, Molecular Pharmacology, Membrane Structural Biology, Translational Therapeutics Physiology and Biophysics Systems Biology & Bioinformatics From Discoveries to Cures

6. SOM Ph.D. Entry Routes • 1. Biomedical Sciences Training Program – BSTP • 2. Medical Scientist Training Program – MSTP • Dual-degree – M.D./Ph.D. • 3. Direct Admission to programs From Discoveries to Cures

7. PhD: Biomedical Sciences Training Program Students enter together, then earn a PhD in one program First semester: cell & molecular biology Lab rotations with prospective advisors From Discoveries to Cures

8. PhD: Biomedical Sciences Training Program Over 200 faculty advisors Smaller labs with individual attention From Discoveries to Cures

9. Typical Progress in Biomedical PhD Program First and Second Years: Initial Recruit coursework, grades rotations selection of thesis advisor At the end of the second year: Candidacy Exam = Qualifier Third Year, plus: Doctoral Candidate publish journal papers fellowships go to conferences thesis and oral defense career goal-setting End of Fifth Year: Graduate and Go On From Discoveries to Cures

10. CWRU MSTP NIH funded Medical Scientist Training Program, 1956 2 years medical school + 4 years PhD + 2 years clerkships Accept about a dozen students/year From Discoveries to Cures

11. Master Programs at CWRU SOM MS in Anesthesia MS Genetic Counseling MS Applied Anatomy MS Public Health Nutrition MS in Biochemical Research MS Coordinated Dietetic MS in Biochemistry MS in Pathology MA in Bioethics MS in Pharmacology MS in Engineering MS in Medical Physiology MS in Clinical Research MS Degree in Translation Bioinformatics MS Environmental Health Science JD/MS in Biochemistry MS in Biostatistics MD/MS Biomedical Investigation Master of Public Health (MPH) MD/MA in Bioethics From Discoveries to Cures

12. SOM Graduate Students, Steady State 2013 SOM PhD students SOM Masters students Total URM Female Male Citizen Foreign n 348 36 179 169 272 76 % 100 10.3 51.4 48.6 78.2 21.8 n 535 58 309 226 466 69 % 100 10.8 57.8 42.2 87.1 12.9 From Discoveries to Cures

13. Ph.D. Time to Degree and Publications 2002-2007 2008-2013 ave TTD ave # pubs/program # pubs/grad Ave primary pubs/program primary pubs/grad 5.7 103.1 3.8 47.9 1.7 5.5 109.4 3.1 54.7 1.5 From Discoveries to Cures

14. CWRU Institutional Training Grants ~ 7 mil in annual total costs, 70 predoc slots, 33 postdoc slots Training in Geographic Medicine & Infectious Diseases Visual Sciences Training Program Case Urology Translational Research Training Program (CUTRTP) Training in Investigative & Molecular Dermatology Cancer Biology Training Grant Combined Training Program in Digestive Disease Sciences Metabolism Training Grant Training Program in Musculoskeletal Research Molecular Medicine Training Program Immunology Training Program- Predoctoral Integrated Engineering and Rehabilitation Training CWRU Nephrology Training Grant Cardiovascular Research Training Program (CRTP) Predoctoral Training in Neurosciences Interdisciplinary Biomedical Imaging Training Program From Discoveries to Cures

15. Summer Research Internships 8-10 wk lab research Science, career seminars poster session $3,500 stipend Travel, housing About 80 students Deadline Feb1 From Discoveries to Cures

16. Postbaccalaureate Research Education Program NIH funded program to prepare for graduate school One year in dynamic research lab Math or science courses GRE workshop and practice sessions From Discoveries to Cures