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Types of stem cells

Types of stem cells. Totipotent: have unlimited capability. Can develop to all postembryonic tissues and organs. Pluripotent: stem cells capable of giving rise to most tissues of an organism. Multipotent: stem cells that are specialized to give rise to a particular cell type. An aside……

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Types of stem cells

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  1. Types of stem cells • Totipotent: have unlimited capability. Can develop to all postembryonic tissues and organs. • Pluripotent: stem cells capable of giving rise to most tissues of an organism. • Multipotent: stem cells that are specialized to give rise to a particular cell type.

  2. An aside…… MACS is used in clinical setting to isolate BM stem cells Bone marrow stem cells have been studied for many years Identified on basis of expression of CD34 Very few found in BM, but only need very few cells to reconstitute immune system

  3. A breakthrough! Induced pluripotent stem cells http://www.pbs.org/wgbh/nova/sciencenow/0305/03.html http://www.sigmaaldrich.com/life-science/stem-cell-biology/ipsc.html

  4. Applications Now that we have our stem cells, what do we do with them? • Cloning – make new organism • Cell therapy – replace damaged tissues • Cell therapy/gene therapy – replace or change defective • tissues

  5. from http://jon.visick.faculty.noctrl.edu/120/slides/Lec23/Slide1.htm

  6. Cloning of many animals mice, cows, pigs, monkeys, cats, endangered animals

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