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Welcome to Biotechnology! August 26 th , 2013

Welcome to Biotechnology! August 26 th , 2013. Grab one of each of the following and put your name on it: 1. file folder 2. student information card (fill it out completely) 3. popsicle stick

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Welcome to Biotechnology! August 26 th , 2013

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  1. Welcome to Biotechnology! August 26th, 2013 • Grab one of each of the following and put your name on it: • 1. file folder • 2. student information card (fill it out completely) • 3. popsicle stick • 4. scratch sheet of paper—fold into a tent and write your name on it just like the example on the board and place it in front of you. You will place this name tent in front of your for two weeks until schedule changes are complete. • Materials list—DUE WEDNESDAY • Take 5-10 minutes to fill out this information

  2. Biotechnology Warm Up August 26th, 2013 • Grab a white board and a dry erase marker from the back of the classroom and answer the following questions: • What do you think biotechnology is? • What would you like to learn about in biotechnology? • Think about what you know about DNA and how we are manipulating it today. Can you think of any useful things we have been able to do with biotechnology? • Take 5-10 minutes to answer these to the best of your ability • Now I need a volunteer to come up to the board and write down everyone’s answers

  3. Biotechnology Warm Up AnswersAugust 26th, 2013 • What do you think biotechnology is? • the exploitation of biological processes for industrial and other purposes, esp. the genetic manipulation of microorganisms for the production of antibiotics, hormones, etc. • What would you like to learn about in biotechnology? Answers will vary • Think about what you know about DNA and how we are manipulating it today. Can you think of any useful things we have been able to do with biotechnology? http://www.bio.org/articles/what-biotechnology

  4. Biotechnology What Now?August 26th, 2013 • Environmental Systems explores the nature of science and the natural world. Students examine environmental issues and learn to make informed decisions using scientific problem solving. Specific topics include ecological interactions, matter and energy flow in ecosystems, biodiversity, characteristics and growth of populations, evolution, succession, biogeochemical cycles, soil and land resources, agriculture, waste management, and characteristics of terrestrial biomes. UT@Austin K-12 Ed • Environmental systems involves many hands on activities, including building solar ovens, growing plants, and exploring our natural resources. We also watch a LOT of movies. • Take a vote on who would like to be in an environmental systems class.

  5. Biotechnology Warm Up August 27th, 2013 • Sign in, get your name and place it in front of you on your table • Go get a white board and dry erase marker from the back of the room, and answer the following questions. • What is DNA? • Why is it important? • Write down everything you remember about DNA • Now I need a volunteer to come up to the board and write down everyone’s answer.

  6. Biotechnology August 27th, 2013 • Mrs. Chagra • Website www.ideaprompter.com • Now we will go around the room and introduce ourselves. • On your whiteboard, draw a simple picture that conveys who you are. Then we will go around the room and introduce ourselves Name Something interesting about yourself What you want to do after high school Put all whiteboards and dry erase markers back NEATLY!

  7. Biotechnology Warm Up August 28th, 2013 • Please get your name tent out of the appropriate box and place it in front of you. • What is biotechnology? If you don’t remember talk with a partner for about 1 minute, then I need a volunteer to come to the board and write down the answer. • What do the following have in common? Talk with your partner about what you think they may have in common. tuberculosis Alzheimer’s disease cancer Chlamydia common cold HIV/AIDS Drug abuse Escherichia coli hepatitis Human papilloma virus (HPV) Lyme disease Malaria yellow fever plague

  8. Biotechnology Warm Up AnswersAugust 28th, 2013 • Biotechnology is a broad term that describes several techniques to study and manipulate organisms or their components. • The following are all diseases for which biotechnology companies are trying to develop new vaccines. Many of the new vaccines will be available in the next decade. With vaccine protection, millions of lives would be saved. Vaccine development is one application of some of the laboratory advances in biotechnology. tuberculosis Alzheimer’s disease cancer Chlamydia common cold HIV/AIDS Drug abuse Escherichia coli hepatitis Human papilloma virus (HPV) Lyme disease Malaria yellow fever plague

  9. Biotechnology Agenda August 28th, 2013 Get a whiteboard for each pair. What does a successful classroom look like to you? Brainstorm with your partner for a few minutes. Then write your ideas down on the white board. You can also draw an illustration if you would like. I need a volunteer to come up to the board and write down everyone’s answers.

  10. Biotechnology Warm Up August 29th, 2013 • Please go get your name tent and place it in front of you. • What does “Lab Safety” mean to you? • Have you had or have known of anyone that had a laboratory accident? • Can you name at least 3 proper procedures for laboratory safety? • Can you see any safety equipment located around the room? What is it and what is it for? http://www.youtube.com/watch?v=DWRGSaaKXV4 http://www.youtube.com/watch?v=d_Bj7ZGwk-4 http://www.youtube.com/watch?v=F6NEdcZY2WY http://www.youtube.com/watch?v=C561PCq5E1g http://www.youtube.com/watch?v=xJG0ir9nDtc

  11. Biotechnology Agenda August 29th, 2013 • We will go over the laboratory safety guidelines. You will take a quiz. You will also take this form home to your parents for a signature. This is for a grade and is due TOMORROW!!!!

  12. Biotechnology Warm Up August 30th, 2013 • Please get your name tent and the safety quiz and place it in front of you. • We will go over the test. • I have all the lab safety rule #s on the board. Please pick one, write your name next to it. • Write the rule IN YOUR OWN WORDS on the white board and we will all share them with the entire class.

  13. Biotechnology Agenda August 30th, 2013 • You and a partner will draw a poster that depicts the two rules that you picked. • You must work on this the entire rest of the period. This means that I expect the poster to LOOK like you worked on it the ENTIRE period. Not thrown together during the last 10 minutes. • Please email me the poster or turn it in by the end of the period. Christa.chagra@del-valle.k12.tx.us

  14. Biotechnology Warm Up and Agenda Sept 3rd, 2013 • Please get your name tent and place it in front of you. • We will go through a ppt. on how to properly record in your journals. • If you did not bring a journal, take notes on a piece of paper and add it to your journal at a later time. • As you are taking notes, I will come by and give you a grade for either having your journal or not. 100% if you have it today, 75% for bringing it late.

  15. Biotechnology Warm Up Sept 4th, 2013 Please get your name tent and place it in front of you. Answer the following in COMPLETE SENTENCES: • Write down the proper procedure for writing warm ups in your journals. • Why are there specific procedures for keeping a lab notebook? • Name one famous scientist that we studied yesterday.

  16. Biotechnology AGENDA Sept 4th, 2013 You will take notes on how to read an MSDS Material Safety Data Sheet. You will use your notes to complete a handout on ACETONE! http://www.usmra.com/repository/category/hazardous_chemicals/How_to_read_MSDS_and_labels.pdf

  17. Biotechnology WARM UP Sept 5th, 2013 Place your name tent in front of you. Get your chemical label quizzes out of the box. For your warm up, write down the following questions. Leave enough room between each question to answer the questions. • What is genetically modified food? • http://www.youtube.com/watch?v=jAP6ZtfP9ZQ • What are the five GMO myths? • http://www.youtube.com/watch?v=ptDd9ftNaq8 • What does SANTO have to do with GMOs? • http://www.indiegogo.com/projects/santo-7-13-15-gmo-movie

  18. Biotechnology AGENDA Sept 5th, 2013 We will go over the chemical label quiz and syllabus. You will take a quiz. Answer everything in COMPLETE SENTENCES. There will be 5 points DEDUCTED for each question not answered in COMPLETE SENTENCES. We will TRADE AND GRADE: Write Graded by: Your Name I will also grade the quizzes. If you do not properly mark off questions when wrong, I will subtract 10 points from your quiz.

  19. Biotechnology WARM UP Sept 6th, 2013 Pick up a hand out. Place your name tent in front of you. Please answer the following in complete sentences in your journals, under the last warm up. If you have your syllabus with you, you can use it. • According to the syllabus we went over yesterday, what is the consequence for the first infraction? • What is the consequence for the 2nd infraction? • What is the consequence for the 3rd infraction?

  20. Biotechnology AGENDA Sept 6th, 2013 You will complete the handout while watching the following video: http://www.youtube.com/watch?v=mH0jL5njNFI http://www.youtube.com/watch?v=GKm2Ch3-Myg

  21. Biotechnology WARM UP Sept 9th, 2013 Pick up a packet. Place your name tent in front of you. Please answer the following in complete sentences in your journals, on a new page, write the day and date. • In a COMPLETE SENTENCE, name a reason why it may not be a good idea to eat genetically modified organisms. • How long have humans been eating genetically modified foods? • As far as you can tell, how does Bill Nye feel about genetically modified organisms?

  22. Biotechnology AGENDA Sept 9th, 2013 You will read chapter 1. I will go over a ppt. You will answer questions from the chapter.

  23. Biotechnology WARM UP Sept 10th, 2013 Place your name tent in front of you. Please answer the following in complete sentences in your journals, under the last warm up. • What is biotechnology? • What does transgenic mean? • Name three common foods that we eat that are genetically modified.

  24. Biotechnology WARM UP Sept 10th, 2013 • What is biotechnology? Biotechnology is the study and manipulation of living things or their component molecules, cells, tissues, or organs. • What does transgenic mean? Transgenic means being or used to produce an organism or cell of one species into which one or more genes or another species have been incorporated. • Name three common foods that we eat that are genetically modified. Three common foods that have been genetically modified are corn,soy and tomatoes.

  25. Biotechnology AGENDA Sept 10th, 2013 You will define 18 vocabulary words from chapter 1 in your journals. You will define these words from the chapter and then define them in your own words. You will also create a small illustration to represent that word in your journals.

  26. Biotechnology WARM UP Sept 11th, 2013 Place your name tent in front of you. Please answer the following in complete sentences in your journals, under the last warm up. • How do we use biotechnology to modify denim jeans? • How do bacteria grow resistant to antibiotics? • What are the 4 major domains of biotechnology?

  27. Biotechnology WARM UP Sept 11th, 2013 • How do we use biotechnology to modify denim jeans? Biotechnology is used to modify denim jeans by genetically engineering enzyme products that break down the cotton fibers to create the stone-washed look. • How do bacteria grow resistant to antibiotics Bacteria grow resistant to antibiotics because antibiotics are being so commonly used and many people do not finish the proper dosage, allowing the most resistant bugs to live and proliferate. • What are the 4 major domains of biotechnology? The 4 major domains of biotechnology are industrial and environmental biotechnology, medical and pharmaceutical biotechnology, agricultural biotechnology, and diagnostic research biotechnology.

  28. Biotechnology AGENDA Sept 11th, 2013 LAB 1 Using the handout I have provided you, answer the following questions in your journals: • Name three types of measurements. • What system do scientists use for measurements? • What is one tool that we use to measure volume? Draw a picture of it with water in it and include a meniscus. • What is one tool that we use to measure mass? Draw a picture of it with the three balances showing a measurement. • The objects you will be using to measure water displacement are three similar sized blocks of different substances. • What three objects will you be using to measure mass? • What will you use to measure distance? • To measure length, you will measure a penny, a paper clip and a book. You will measure each item with a meter stick and a ruler. AS SOON AS YOU HAVE FINISHED ANSWERING THE QUESTIONS ABOVE, PLEASE RAISE YOUR HAND, I WILL STAMP YOUR WORK AND SIT QUIETLY UNTIL EVERYONE IS FINISHED.

  29. Biotechnology AGENDA Sept 11th, 2013 LAB 1 Answer the questions for the pre-lab and we will do the lab tomorrow.

  30. Biotechnology WARM UP Sept 12th, 2013 Place your name tent in front of you. Please answer the following in complete sentences in your journals, under the last warm up. • What is Escherichia coli? • What is the difference between old biotechnology and new biotechnology? • What are antibiotics?

  31. Biotechnology WARM UP Sept 12th, 2013 • What is Escherichia coli? Escherichia coli is a bacteria that is commonly found in the lower intestine of warm-blooded organisms. We use E. coli to produce many human proteins. • What is the difference between old biotechnology and new biotechnology? Old biotechnology includes selective breeding and the fermentation of certain foods and beverages. New biotechnology includes the ability to “cut and paste” DNA pieces from one organism and place them into another. • What is an antibiotic? An antibiotic is a chemical substance produced by one organism that is destructive to another. The word comes from antibiosis a term coined in 1889 by Paul Vuillemin which means a process by which life could be used to destroy life.

  32. Biotechnology AGENDA Sept 12th, 2013 Taking Proper Measurements. You will rotate between each station and measure using various measuring devices and techniques.

  33. Biotechnology WARM UP Sept 13th, 2013 Place your name tent in front of you. Please answer the following in complete sentences in your journals, under the last warm up. • What are restriction enzymes? • What is DNA ligase? • What does the human gene t-PA do?

  34. Biotechnology WARM UP Sept 13th, 2013 • What are restriction enzymes? Restriction enzymes are enzymes that cut pieces of DNA at or near a specific sequence of bases. These are produced chiefly by certain bacteria. • What is DNA ligase? DNA ligase is an enzyme that pastes pieces of DNA together to create new combinations of DNA information. • What does the human gene t-PA do? The human gene t-PA produces a blood-clot dissolving enzyme.

  35. Biotechnology WARM UP Sept 16th, 2013 What did you notice about taking measurements for our lab on Friday? Did each person make the same measurement for each station? Why could measurements be different if two people are measuring the same item?

  36. Biotechnology WARM UP Sept 16th, 2013 • What did you notice about taking measurements for our lab on Friday? I couldn’t remember how to use a triple beam balance • Did each person make the same measurement for each station? Some people’s measurements were different. • Why could measurements be different if two people are measuring the same item? People estimated different values Errors in Measurements

  37. Biotechnology AGENDA Sept 16th, 2013 Do you have any questions over what we have covered this far? syllabus lab safety E. coli restriction enzymes GMOs CAFOs taking proper measurements TEST

  38. Biotechnology WARM UP Sept 17th, 2013 We will go through our lab results from Friday. We will demonstrate proper data collection techniques: DATA TABLE: Paper Clip Measurements Answer the following questions in your journals: • What is the difference between precise and accurate? • Which station had the largest discrepancies in measurements? Why? • What questions from the quiz yesterday did you not know the answer to? • http://www.youtube.com/watch?v=qzfS1Z4Aec0

  39. Biotechnology AGENDA Sept 17th, 2013 You can also take this time to update your journals-including your TABLE OF CONTENTS. 5-8 minutes, and WRITE A CONCLUSION. When you are finished, you can get started on the vocabulary for Chapter 1, sections 2-8. AFTER YOU HAVE DEFINED ALL THE WORDS AND DRAWN A MINI PICTURE, You and a partner will pick two vocabulary words and define them and draw them on a sheet of paper with markers or colored pencils to be displayed in the room.

  40. Biotechnology WARM UP Sept 18th, 2013 Using the Biotech handout, answer the following questions: 1. What would be a benefit to create round-up ready (herbicide resistant) soybeans, corn or cotton? 2. Why would a growth hormone for cows (Posilic bovine somatotropine) be beneficial to farmers? 3. Why would a company want to create a virus-resistant papaya?

  41. Biotechnology WARM UP Sept 18th, 2013 Using the Biotech handout, answer the following questions: • What would be a benefit to create round-up ready soybeans, corn or cotton? Round up ready soybeans, corn or cotton will be able to resist the herbicide round up. Therefore the farmers can use as much round up to kill the unwanted weeds in their fields, but not the valuable crop. • Why would a growth hormone for cows (Posilic bovine somatotropine) be beneficial to farmers? This grown hormone allows the cows to have a higher yield of milk production. • Why would a company want to create a virus-resistant papaya? The virus wiped out many acres of papaya production. Introduction of the transgenic papaya has allowed for continued papaya production.

  42. Biotechnology AGENDA Sept 18th, 2013 YOU WILL WRITE A VOCABULARY WORD WITH A DEFINITION AND A PICTURE! MAKE IT LOOK LIKE SENIOR WORK. YOU ARE MAKING ME A WORD WALL. Bovine growth hormone- Posilac bovine somatotropin A growth hormone that enables lactating cells in dairy cows live longer to produce more milk.

  43. Biotechnology WARM UP Sept 19th, 2013 Using the Biotech handout, answer the following questions: 1. When would it beneficial for doctors to use genetically engineered t-PA? 2. What animal do they use to make t-PA? 3. Draw the diagram on page 12 in your journals and describe the process of engineering the human t-PA gene.

  44. Biotechnology WARM UP Sept 19th, 2013 Using the Biotech handout, answer the following questions: • When would it beneficial for doctors to use genetically engineered t-PA? Doctors use t-PA in patients that have had a heart attack to clear blocked blood vessels. • What animal to they use to make t-PA? Researchers genetically engineer mammalian cells using Chinese hamster ovary cells. • Draw the diagram on page 12 in your journals and describe the process of engineering the human t-PA gene.

  45. Biotechnology AGENDA Sept 19th, 2013 You will define and interpret the vocabulary words from Chapter 1 section 1.2-1.8 by writing the definitions in your journals IN YOUR OWN WORDS with a corresponding illustration to demonstrate your understanding of the vocabulary word. Ex.: Bovine growth hormone- (Posilacbovine somatotropin) A growth hormone that enables lactating cells in dairy cows live longer to produce more milk.

  46. Biotechnology WARM UP Sept 20th, 2013 Using the Biotech handout, answer the following questions: • Why would a biotechnology company specialize in particular product area? • What are the questions that must be answered in a “product development plan?” Just write the first question in each area.

  47. Biotechnology WARM UP Sept 20th, 2013 Using the Biotech handout, answer the following questions: • Why would a biotechnology company specialize in particular product area? Companies can specialize in a particular product area because the manufacturing processes and procedures are nearly the same among similar products. The protocols for manufacturing recombinant growth hormone are almost identical to those for producing recombinant human insulin. • What are the questions that must be answered in a “product development plan?” Does the product meet a critical need? Is the market large enough to produce enough sales? Do preliminary data support that the product will work? Can patent protection be secured? Can the company make a profit?

  48. Biotechnology AGENDA Sept 20th, 2013 Please read pages 10-14, then answer the questions on page 14: • Name two antibiotics used as medicines. • The use of what kind of enzymes allows scientists to cut and paste pieces of DNA together to form recombinant DNA? (There are two, one to cut and one to paste together) • Explain how making human tissue plasminogen activator (t-PA) in CHO cells is an example of genetic engineering in detail! I need at least a one page explanation.

  49. Biotechnology WARM UP Sept 23rd, 2013 Please pick up the Biotechnology Packet Sections 1.2-1.8 and answer the following questions in your journals. • A drug discovery process can take nearly 15 years. Explain why it takes so long to bring a new drug to market. • Does every product in research and development make it to market? Yes or no? Explain.

  50. Biotechnology WARM UP Sept 23rd, 2013 Please pick up the Biotechnology Packet Sections 1.2-1.8 and answer the following questions in your journals. • A drug discovery process can take nearly 15 years. Explain why it takes so long to bring a new drug to market. Each company’s pipeline is reviewed regularly in light of the product development plan. If the answers to the questions are unsatisfactory, the company will pull the product from the pipeline. If the product is a pharmaceutical product it has to go through Phase III clinical trials with thousands of patients included in the testing before the FDA will approve the product. • Does every product in research and development make it to market? Yes or no? Explain. No, it may be learned early in research and development that a potential product is too costly to produce. That product may pulled form the pipeline early on before the company has invested too many resources in its development.

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