Colimix 120 Sintofarm (Colistinsulphate)
Colistin is a polypeptide antibiotic , was obtained from a fermentation broth inoculated with Bacillus polimyxa var. colistinus which had been isolated from soil sampled of Fukushima Prefecture , Japan.
Colimix 120 Sintofarm Anti-bacterial spectrum Gram-negative : E.Coli Shigella spp Salmonella spp Enterobacter spp Pseudomonas aeruginosa Klebsiella pneumoniae Campylobacter (vibrio) coli .
Colimix 120 Sintofarm Characteristics : Colistin is effective against Gram – bacteria such as E.Coli and Salmonella. Colistin does not select resistant bacteria in vivo and its resistance is not transferred by the R-factor. Colistin is not absorbed from the digestive tract of poultry hence no residue is observe. Colistin has a synergistic effect against bacteria when used in combination with Zinc-bacitracin. Colistin is effective as a growth promoter for broiler. It is also used in the prevention and control of infectious enteritis in broiler.
Colimix 120 Sintofarm Synergism and Antagonism : Colistin is compatible with tetracyclines, sulfas, imidazoles, Lincomycin and common feed additives. Sometimes is showed a good synergism with some antibiotics particularly with bacitracin .There are no experiences of antagonist effects between Colistin and other antibiotics. Palatability : No "medicinal taste" to deter sick animals from eating or drinking.
Colimix 120 Sintofarm + Zinc bacitracin Colistin Sulphate premix Combination use of Colistinsulphate and Zinc bacitracin show the followings: They have a mutually compensating antibacterial spectrumn. Synergistic action against many bacteria in the digestive tract
Colimix 120 Sintofarm Colimix 120 premix is : For prevention and control of infectious enteritis in broilers and layers .(E.Coli,Salmonella) For improving feed efficiency and weight gain. Colimix 120 premix is a barrier against enteritis from E.Coli and Salmonella in poultry
Colimix 120 Sintofarm • Colimix 120 pemix is : • SAFE • Because it is not absorbed • Because it leaves no residues in the meat • Because it does not present problem of resistance • Because it does not present problem of toxicity • Because it can be associated with all other antibiotics and sulfa –drugs • STABLE • In the premix for 12-24 months • In the feed for at least 6 months • In mineral feed for at least 4 months
Colimix 120 Sintofarm Effective • Because of its activity against Gram - bacteria , specially E.Coli and Salmonella , even if they are resistant to other antibacterial substances • Because it not only checks but treats the disease • Because it improves animal performance • Because of its bactericide action at low dosage(5-8 mg /kg live weight) • Because it acts rapidly and can be used in periods when the sanitary risk is higher
Colimix 120 Sintofarm Poultry : For prevention of intestinal diseases (diarrhea) 20-200 g/ton of complete feed . Poultry : For therapy 800-1000g/ton of complete feed for 5-15 days
Colimix 120 Sintofarm Composition for kg : Colistinsulphate 120 g Carrier up to 100 g Withdrawal period : 5 days Storage : keep in dry place and avoid light Shelf life : 24 months Packaging : 25 kg bags
Colimix 120 Sintofarm Colimix 120 premix Sintofarm has : 1)Broad antibiotic spectrum – has strong activity on gram-negative bacteria such as E.Coli , Salmonella ecc. 2)Strong bactericidal capacity-its effect mechanism is to block cell membrane selective permeation function. 3)Good compatibility- better effectiveness in combination with gram-positive bacteria drug 4)Good stability-it is not affected by feed ,enzyme and secretive substance. 5)Good security- no side effect , no residue