1 / 21

Prostatic Carcinoma

Prostatic Carcinoma. Jakob, 8 yo MC Beagle. History. Diagnosed with prostatic carcinoma 8/26/10 by cytology from ultrasound guided prostatic aspirate done by an internist in Richmond. Originally presented to rDVM for abdominal/hind end pain.

ruby-small
Download Presentation

Prostatic Carcinoma

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Prostatic Carcinoma

  2. Jakob, 8 yo MC Beagle

  3. History • Diagnosed with prostatic carcinoma 8/26/10 by cytology from ultrasound guided prostatic aspirate done by an internist in Richmond. Originally presented to rDVM for abdominal/hind end pain. • Referred to NCSU Oncology for further evaluation & treatment on 8/30/10. Chest radiographs were clear. A focused ultrasound was done for baseline pre-treatment measurements and showed extension of the mass into the urethra. • Chemotherapy protocol of Mitoxantrone and Piroxicam was initiated at the initial visit. • Jakob has received regular recheck chest radiographs and abdominal/focused ultrasounds approximately every 1.5 mo to monitor his disease and response to treatment

  4. Significant Clinical & Laboratory Findings 2/14/11: • Physical Exam • TPR: WNL • CVR: audible low 3rd heart sound (hx of mild MR & TR, mild-mod AR/endocardiosis) • ABD: Mild hepatomegaly • Rectal: Prostate firm and bliaterally enlarged (R>>L), non-painful on palpation, anal sacs normal, normal stool • CBC: WNL

  5. Focused Prostatic Ultrasound

  6. Mineralization

  7. Mineralization

  8. Prostate Right Transverse

  9. Prostate & Urethra

  10. Prostate Tracing

  11. Prostate Tracing

  12. Thoracic Radiographs

  13. Thoracic Radiographs

  14. Assesment • Prostate has increased in size <10% = stable disease….. • EXCEPT…… • Thoracic radiographs showed new nodules =progressive disease

  15. Outcome • Jakob is doing well and is not currently exhibiting clinical signs of his disease (no straining to urinate/defecate) • He does progressive disease which means he has “failed” Mitoxantrone chemotherapy. • He was switched to Carboplatin at the 2/14/11 visit

  16. Other Differential Diagnoses • Alternative appearance of Prostatic Carcinoma • Benign Prostatic Hyperplasia • Prostatitis

  17. Prostatic carcinoma (again!)

  18. Benign Prostatic Hyperplasia (BPH)

  19. Prostatitis

  20. Prostatitis

  21. How do you differentiate? • Signalment • BPH: Intact or recently neutered (within 1 year) • Prostatitis: usually younger males, but can be any age • Neoplasia: usually middle to older animals. High index of suspicion with a large prostate in an older long ago neutered male • Get a sample • Cytology/histopathology needed for a confirmed diagnosis of neoplasia • Prostatic wash with culture to rule in/out prostatitis • Neuter! • If strongly suspect BPH or have ruled out other causes neutering should reduce the size of the prostate in BPH but can take a while to see size reduction

More Related