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Fig. S1

Fig. S1. + leu. - leu. A. 5. *. 4. 3. Serum TSH (ng/ml). 2. 1. 0. Fig. S2. + leu. - leu. B. A. 4. 26. *. *. 3. #. 24. Average Body Weight (g). *. 2. Average Food Intake (g). *. 22. 1. 20. 0. -. -. +. +. TRH Ab. TRH Ab. Fig. S3. - leu/ + TRH Ab/ + T3.

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Fig. S1

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  1. Fig. S1 + leu - leu A 5 * 4 3 Serum TSH (ng/ml) 2 1 0

  2. Fig. S2 + leu - leu B A 4 26 * * 3 # 24 Average Body Weight (g) * 2 Average Food Intake (g) * 22 1 20 0 - - + + TRH Ab TRH Ab

  3. Fig. S3 - leu/ + TRH Ab/ + T3 - leu/ + TRH Ab/ - T3 - leu/ - TRH Ab/ - T3 B A 4 * 26 # 25 3 # Average Body Weight (g) 24 2 Average Food Intake (g) 23 1 22 21 0

  4. Fig. S4 + leu - leu B A 4 26 # * 3 * * 24 Average Body Weight (g) * 2 Average Food Intake (g) 22 1 0 20 - - + + Ad-shCREB Ad-shCREB

  5. Fig. S5 - leu/ + shCREB/ + TRH - leu/ + shCREB/ - TRH - leu/ - shCREB/ - TRH B A 30 3.0 * # 20 2.0 Average Body Weight (g) Average Food Intake (g) 10 1.0 0 0

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