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This document provides a comprehensive overview of target domains and structure, highlighting key mutations, RNA interference (RNAi), and clinical candidates in drug development. It explores interaction networks and pathways associated with druggable targets, cancer cell line sensitivity, and bioactivity profiles. Additionally, it details the complexity of 3D interactions among compounds and emphasizes the significance of copy number variation in expression analysis. Overall, it serves as a critical resource for understanding drug discovery and optimizing therapeutic strategies.
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Target banner T G T G C C C C * *
Target synopsis side panel Overview Domains and structure Chemistry Family T G T G T G T G C C C C C C C C * * * * Mutation
Target synopsis side panel RNAi Drugs and clinical candidates C C C C Interaction networks Cell line matrix
Target synopsis side panel Pathway Expression Copy number variation Druggabiliy
Compound banner 5 5 ! ! C C ORAL ORAL
Compound synopsis side panel Data summary Bioactivity profile Cell line sensitivity 3D complexes
Cell line banner T G T G C C C C * *
Cell line synopsis side panel RNAi Mutation Drug sensitivity T G T G T G T G C C C C C C C C * * * * Similar cell lines
5 S ! C C ORAL T G C C *