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Overview of Target Drug Candidates and Their Molecular Interactions

This document provides a comprehensive overview of target domains and structure, highlighting key mutations, RNA interference (RNAi), and clinical candidates in drug development. It explores interaction networks and pathways associated with druggable targets, cancer cell line sensitivity, and bioactivity profiles. Additionally, it details the complexity of 3D interactions among compounds and emphasizes the significance of copy number variation in expression analysis. Overall, it serves as a critical resource for understanding drug discovery and optimizing therapeutic strategies.

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Overview of Target Drug Candidates and Their Molecular Interactions

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  1. Target banner T G T G C C C C * *

  2. Target synopsis side panel Overview Domains and structure Chemistry Family T G T G T G T G C C C C C C C C * * * * Mutation

  3. Target synopsis side panel RNAi Drugs and clinical candidates C C C C Interaction networks Cell line matrix

  4. Target synopsis side panel Pathway Expression Copy number variation Druggabiliy

  5. Compound banner 5 5 ! ! C C ORAL ORAL

  6. Compound synopsis side panel Data summary Bioactivity profile Cell line sensitivity 3D complexes

  7. Cell line banner T G T G C C C C * *

  8. Cell line synopsis side panel RNAi Mutation Drug sensitivity T G T G T G T G C C C C C C C C * * * * Similar cell lines

  9. 5 S ! C C ORAL T G C C *

  10. S

  11. View ligand interactions

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