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Trisynaptic Circuit

Trisynaptic Circuit. Hippocampal-Cortical Circuitry. AMNESIA……. …………..NOT A SOAP OPERA. Hypoxia; hippocampus: Another area of selective vulnerability is the hippocampus. In this slide the hippocampus is shrunken, cavitated and discolored, the result of a severe episode of hypoxia.

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Trisynaptic Circuit

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  1. Trisynaptic Circuit

  2. Hippocampal-Cortical Circuitry

  3. AMNESIA…… …………..NOT A SOAP OPERA

  4. Hypoxia; hippocampus: Another area of selective vulnerability is the hippocampus. In this slide the hippocampus is shrunken, cavitated and discolored, the result of a severe episode of hypoxia. • Next Slide will show a damaged hippocampus…..

  5. Korsakoff’s Syndrome –Degeneration of Mammillary Bodies

  6. Recall of famous faces

  7. Basal Ganglia

  8. Rat hippocampus

  9. Hippocampal place field

  10. ‘Cognitive Map’ Dostrovsky & O’Keefe (1971)

  11. Frontal Cortex

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