TCR and T lymphocyte development in thymus Preloader

TCR and T lymphocyte development in thymus - PowerPoint PPT Presentation


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Students should know:. Structure of TCRsCDRsDifferences of recognized antigen between TCR and immunoglobulins (Ig)TCR germ line configuration and rearrangementsTCR specificityClonality of T cellsDifferences between TCR a and b chainsT cell receptor gene rearrangement and lineage commitmentpreTCRPositive selectionNegative selectionChanges in CD4/CD8 expression during T cell maturation in thymus.The order and location of T cell selectionCell types involved in T cell selectionWhy is197

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