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RNA & Central Dogma. What does DNA stand for? Based on your answer to #1, predict what RNA stands for? What is the complementary DNA strand to this sequence GTA ATC ATA? Draw and label a picture of a nucleotide. Who are Watson & Crick & what do they have to do with DNA? .
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What does DNA stand for? Based on your answer to #1, predict what RNA stands for? What is the complementary DNA strand to this sequence GTA ATC ATA? Draw and label a picture of a nucleotide. Who are Watson & Crick & what do they have to do with DNA? Bellwork- have slate, marker & eraser on desk
Announcements Bio 1-2: Is your science fair board turned in? PreAP: BLAST handout get ratHBB from class website @ home DietrichBiology.wikispaces.com due date changed to next Tues. 1-28-14 Everyone: This is a block week, so Friday is…. Everyone: Pass out slates for today
Central Dogma (“Big Idea”) of Biology DNA stores information to run cell DNA RNA Protein
DNA vs RNA • How many nucleotides? • 3 parts of a nucleotide? • What does the “B” stand for? Deoxyribonucleic Acid
DNA vs RNA What’s the difference? • How many nucleotides? • 3 parts of a nucleotide? • What does the “B” stand for? OH! Deoxyribonucleic Acid Ribonucleic Acid
Remember this? Structure is related to function! What are DNA’s 2 functions?
RNA Structure Notes • RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)
RNA Structure Notes • RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose) • In RNA, the nitrogenous bases are G,C,A and U (no T)
RNA Structure Notes • RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose) • In RNA, the nitrogenous bases are G,C,A and U (no T) • RNA is usually single-stranded
Vote by sign language: NA NA RNA DNA DNA AGCCTGCTA TCGGACGAT RNA RNA
Try this • What might it look like if you turned this double stranded DNA molecule into an RNA copy? AGTTCGA TCAAGCT RNA: UCAAGCU Which DNA strand would this RNA be the COMPLEMENT of?
Try this • What might it look like if you turned this double stranded DNA molecule into an RNA copy? AGTTCGA TCAAGCT RNA: UCAAGCU AGUUCGA Which DNA strand would this RNA be the COMPLEMENT of? Do the RNA complement for the bottom DNA strand
DNA vs RNA RNA has a different structure… predict it’s functions (jobs) Hint: other names for RNA messenger RNA ribosomal RNA transfer RNA
Central Dogma (“Big Idea”) of Biology DNA stores information to run cell DNA RNA’s function is to make proteins! RNA Protein
Why are proteins so important? • Proteins are made of tiny subunits…what are they called? • What are some functions of proteins? (Hint: ) • Chemical Reactions (enzymes) • Immune System (antibodies) • Growth & Development (hormones) • etc.
Central Dogma (“Big Idea”) of Biology DNA stores information to run cell DNA RNA’s function is to make proteins! RNA Proteins actually DO the work in the cell Protein
Types of RNA • mRNA:messenger RNA makes a copy (message) of the information stored in DNA & moves the info out of the nucleus! (DNA doesn’t leave nucleus) Codons are 3 letter “words” that make up the message- it’s a recipe for a protein
Types of RNA • rRNA:ribosomal RNA folds into a ribosome which reads the mRNA codons and connects amino acids into a chain that will become a protein Realistic image of rRNA folded into a ribosome rRNA folds into 2 subunits (large & small) Together, they make the ribosome!
Types of RNA • tRNA:transfer RNA transports amino acids to the ribosome, and uses an anti-codon to match the correct amino acid to the correct mRNA codon. It then transfers amino acids to the growing chain. tRNA is T-shaped!
