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Laboratory Information Management System, LRN & Surveillance

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  1. Laboratory Information Management System, LRN & Surveillance Enhancing Seasonal Influenza Surveillance Austin, Texas Todd Lasco Texas Department of State Health Services Laboratory Services Section

  2. LIMS - Current Status • Today - “Go-Live” Virology, Mycobacteriology and Consumer Microbiology Laboratory use at the Austin & South Texas Laboratories • Cohort >> LabWare LIMS • User roles via Citrix > those external to DSHS 1) Epidemiologist 2) Submitter

  3. DSHS Lab Contact Liz Delamater, Ph.D. Manager, Microbiological Sciences Branch Texas Department of State Health Services 1100 West 49th Street Austin, TX 78756 512-458-7592 (office) Elizabeth.Delamater@dshs.state.tx.us

  4. Laboratory Response Network • Established in response to Presidential Decision Directive 39 • Founding partners: Centers for Disease Control and Prevention (CDC), Association of Public Health Laboratories (APHL), and Federal Bureau of Investigation (FBI) • Operational in August 1999

  5. LRN Mission • Provide infrastructure to increase laboratory capacity • Respond to biological and chemical threat agents and other public health emergencies • 150+ state and local public health, federal, military, food testing, veterinary, environmental, and international laboratories

  6. LRN Structure Definitive characterization of the most deadly infectious agents Confirmatory testing for most select agents Rule-out testing and referral of specimens

  7. Where We Started: 1999 • 6 Laboratories • 1 Level C • 5 Level B • 1 Dedicated technician/lab • 2 Real-time PCR machines • Austin & San Antonio

  8. Wichita Falls Lubbock Dallas Ft. Worth El Paso Tyler Austin Houston San Antonio Laredo Corpus Christi Harlingen Texas LRN Locations

  9. Texas LRN Laboratories • 11 Laboratories • 10 Confirmatory laboratories each w/ BSL-3 facilities • 1 BSL-2 laboratory capable of confirming B. anthracis and Y. pestis only • Laredo 2009 • Real-time PCR and Time-Resolved Fluorescence (TRF) platforms in each confirmatory laboratory (10)

  10. Texas LRN Influenza Testing • Avian H5 primer/probe sets – LRN • Flu A, Flu B, H1, H3, H7 primer/probe sequences - APHL • Houston, Tarrant County & Dallas LRNs

  11. Pilot • Establish greater connectivity between our sentinel labs and our regional LRNs • Insert our regional LRNs into the loop of testing/routing samples here to DSHS for viral isolation such that that particular LRN or LRNs can provide a quicker TAT and feedback to the submitter through PCR testing at their site • Test Labware LIMS functionalities

  12. Texas LRN Contacts

  13. Contact Information Todd Lasco Texas Department of State Health Services Laboratory Services Section MC 1947P.O. Box 149347Austin, TX 78714-9347Ph: 512.458.7111 (x3535) Fx: 512.458.7431 Todd.Lasco@dshs.state.tx.us

  14. Questions?