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Fig. S1. A. TG mice. NTG. Plasmid control. 10 copy. 100 copy. 1 copy. NTG. NTG. 36. 41. 74. 76. 78. 90. 97. 98. 105. Enzyme : Eco-RI. I2020T LRRK2: 3,404 bp. B. 10K. Bgl II. Eco RI. 8. 41. 74. B6. 41. 74. B6. 6. 5. 4. 3. 2.5. 2. 1.5. 1.

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  1. Fig. S1 A TG mice NTG Plasmid control 10 copy 100 copy 1 copy NTG NTG 36 41 74 76 78 90 97 98 105 Enzyme: Eco-RI I2020T LRRK2: 3,404 bp

  2. B 10K Bgl II Eco RI 8 41 74 B6 41 74 B6 6 5 4 3 2.5 2 1.5 1 Tandem LRRK2: 2310 bp (Eco RI) 2474 bp (Bgl II) 0.75

  3. Fig. S2 NTG TG NTG TG NTG TG Wb St Mb

  4. Fig. S3 NTG TG ** TH Fluorescence intensity of LRRK2 LRRK2 Overlay Scale bar:10μm

  5. Fig. S4 ** * * (wks) 34 42 59 34 42 59 34 42 59 34 42 5934 42 59 day1 day2 day3 day4 day5 Training session

  6. Fig. S5

  7. Fig. S6 Blind Visible Blind Visible NTG TG

  8. Fig. S7 V5 GM130 Overlay

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