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LINCS. Meeting Goals and Expected Outcomes of LINCS Consortium Jennie Larkin. LINCS. LINCS Meeting Goals. LINCS Phase 1 Activities Large-scale production of perturbation-induced molecular and cellular signatures

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lincs
LINCS

Meeting Goals and Expected Outcomes of LINCS Consortium

Jennie Larkin

LINCS

lincs meeting goals
LINCS Meeting Goals

LINCS Phase 1 Activities

  • Large-scale production of perturbation-induced molecular and cellular signatures
  • Creation of a database, common data standards and public user interface for accessing the data
  • Computational tool development and integrative data analyses
  • Development of new cost-effective, molecular and cellular phenotypic assays
  • Integration of existing datasets into LINCS

LINCS

lincs meeting goals1
LINCS Meeting Goals

Establish the LINCS consortium

  • Learn other’s research
  • Identify joint areas of interest
  • Establish a joint project with one or more groups

Identify common LINCS challenges

  • How to integrate multi-dimensional assays into a single coherent LINCS database?
  • How to mine and analyze LINCS data?
  • How to encompass more biomedical research areas into LINCS?
  • How to leverage other activities?

LINCS

lincs meeting goals2
LINCS Meeting Goals

Establish the LINCS consortium

  • Learn other’s research
  • Identify joint areas of interest
  • Establish a joint project with one or more groups

Identify common LINCS challenges

  • How to integrate multi-dimensional assays into a single coherent LINCS database?
  • How to mine and analyze LINCS data?
  • How to encompass more biomedical research areas into LINCS?
  • How to leverage other activities?

LINCS

lincs1
LINCS

LINCS

lincs consortium members
LINCS consortium members

Califano U01

Califano U01

Jaffe

U01

Meldrum U01

Broad U54

Medvedovic U01

Miller-Jensen U01

HMS U54

Schurer

U01

LINCS

Zhou

U01

Snyder

Mootha

& Bao

lincs identifying initial groups
LINCS identifying initial groups

Califano U01

Califano U01

Jaffe

U01

Meldrum U01

Broad U54

Medvedovic U01

Miller-Jensen U01

HMS U54

Schurer

U01

LINCS

Zhou

U01

Snyder

Mootha

& Bao

lincs building the consortium
LINCS building the consortium

Califano U01

Califano U01

Jaffe

U01

Meldrum U01

Broad U54

Medvedovic U01

Miller-Jensen U01

HMS U54

Schurer

U01

LINCS

Zhou

U01

Snyder

Mootha

& Bao

lincs building the consortium1
LINCS building the consortium

Califano U01

Califano U01

Jaffe

U01

Meldrum U01

Broad U54

Medvedovic U01

WG

Miller-Jensen U01

HMS U54

WG

Schurer

U01

LINCS

Zhou

U01

WG

  • Identify common interests
  • Identify key collaborations
  • Join/form working groups

Snyder

Mootha

& Bao

lincs meeting goals3
LINCS Meeting Goals

What can we do in the next 2 years to make LINCS succeed?

LINCS