Ensemble Synchronization in Schizophrenia
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Investigating neural synchronization patterns in schizophrenia patients using EEG data and video analysis. This study explores ensemble synchronization and its implications for understanding the disorder.
Ensemble Synchronization in Schizophrenia
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Presentation Transcript
Electrical Geodesics Inc & Neuroinformatics Center, UO, 15 Nov. 2013 Ensemble Synchronization in Schizophrenia Kaushik Majumdar, ISI Bangalore Joint work with Pradeep D. Prasad (ISI), John P John (NIMHANS), H. N. Harsha (Nitte University) https://sites.google.com/site/isicng/ (Computational Neuroscience Group)
Prasad et al. Clin. EEG Neurosci.44(1): 16 – 24, 2013 Pairwise Hilbert Phase Synchronization
Phase Synchronization Prasad et al. 2012
Videos • Healthy control subject http://youtu.be/4aFMQFhiRHw • Patient with schizophrenia http://youtu.be/-TECG5XQhB4
Classification by Logistic Regression • 3 dimensional feature space: • Ensemble right hemispheric synchronization. • Ensemble left hemispheric synchronization. • Response latency.
2 Dimensional Projection of 3 Dimensional Feature Space Cross is patient with schizophrenia square is healthy control subject Incongruent stimulus
2 Dimensional Projection of 3 Dimensional Feature Space Congruent stimulus Plus is patient with schizophrenia circle is healthy control subject
2 Dimensional Projection of 3 Dimensional Feature Space Neutral stimulus Star is patient with schizophrenia diamond is healthy control subject
Reference • P. D. Prasad, H. N. Halahalli, J. P. John and K. Majumdar, “Single-trial EEG classification using logistic regression based on ensemble synchronization,” accepted in IEEE Journal on Biomedical and Health Informatics.