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Medications

Medications. Chapter 5. Statistics. 2009 Most Prescribed Vicodin Zokor Z estril Levoxyl Zithromax Illicit Drugs Prescription Drugs Projected Prescription Drug Market, 2016-$500 billion !. Side Effects 2005. Serious Adverse Drug Events Fatal Drug Events

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Medications

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  1. Medications Chapter 5

  2. Statistics • 2009 Most Prescribed • Vicodin • Zokor • Zestril • Levoxyl • Zithromax • Illicit Drugs • Prescription Drugs • Projected Prescription Drug Market, 2016-$500 billion !

  3. Side Effects 2005 • Serious Adverse Drug Events • Fatal Drug Events • Drug Approval Process (Page 90) • High Cost to Approve and Manufacture Drugs

  4. Generic Drugs • Patent expires after 20 years, then other companies can manufacture it and it is under its chemical name. • Less expensive as there is no research cost • 2006- $54 billion in generic drug sales • FDA standards are the same for brand name & generics

  5. Generics • Contain essentially identical amts. of identical ingredients in identical doses (Chemical equivalence) • Must perfom in the same manner as the name brand (Bioequivalence) • Must deliver the same amt. of active ingredient into the bloodstream as the name brand (Bioavailability) Generics do not undergo extensive testing & clinical trials

  6. Presecription Drug Abuse (pp. 92-93) • In 2009, 20.2% of students had taken prescription drugs w/o a doctor’s Rx, one or more times in their life. • Internet Prescriptions – • Many require no scripts • 1/5 of internet pharmacies were under investigation (68 internet pharmacies/2004) • Canadian Pharmacies –safe, lower $$, require Rx, banned but no one has been prosecuted for personal use • Counterfeit Drugs- est. $75 billion market

  7. Orphan Drugs • Drugs that treat rare diseases • 6,000 conditions that affect less than 200K citizens • Cost is too high for such a small market • Orphan Drug Act of 1983 offers incentives & tax credits, 7 year monopoly and research grants to encourage drug companies to develop these drugs • 1983-2010, 347 new drugs developed and reached the market (MS, CF, hemophilia, etc)

  8. OTC Drugs • No Script • Self-Directed • Self Diagnosed • Non-habit forming • 100K OTC w/800 significant active ingredients • 178K hospitalizations due to misuse of OTC drugs (Read the label) Interactions with alcohol or other prescription or OTC drugs

  9. Common Pain Relievers • Acetaminophen- overuse = liver damage • Alcohol use increases risk • NSAID (Ibuprofen) • Increase risk of gastric/stomach bleeding especially if over 60 on blood thinners, ulcers, or other bleeding issues. • Can damage kidneys • Above safe if used correctly and sparingly Methamphetamine Production- Pseuoephedrine used in above. 2006 law requires ID and limits purchase. BTC designation added to some OTC drugs in Canada

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