Gastrointestinal medications
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Gastrointestinal Medications. Antacids. Side effects: constipation, diarrhea Interfere with tetracycline absorption OTC meds Ex. Maalox, Mylanta (aluminum hydroxide) Milk of Magnesia (MOM) magnesium hydroxide Magnesium trisulcate ( Gelusil ). H2 Antagonists/blockers.

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Antacids
Antacids

  • Side effects: constipation, diarrhea

  • Interfere with tetracycline absorption

  • OTC meds

  • Ex. Maalox, Mylanta (aluminum hydroxide)

  • Milk of Magnesia (MOM) magnesium hydroxide

  • Magnesium trisulcate (Gelusil)


H2 antagonists blockers
H2 Antagonists/blockers

  • Block gastric acid and pepsin production from stimulation by food of parietal stomach lining cells. These meds block H2 receptors in parietal cells so no acid produced

  • Usually taken at bedtime. Interfere with ASA, ethanol, caffeine and cough meds.


Examples of h2 blockers
Examples of H2 blockers

  • Cimetidine (Tagamet)

  • Rantidine (Zantac)

  • Famotidine (Pepcid)

  • All are oral tablets, OTC in low doses, Rx in higher doses


Proton pump inhibitors new generation antacids replacing h2 blockers
Proton Pump Inhibitors (new generation antacids replacing H2 blockers)

  • Block the ATP of the proton/acid pump of the parietal cells. Active pump in lining which makes acid is stopped by blocking access to ATP

  • Used also for GERD like H2 antagonists


Ex of proton pump inhibitors
Ex. Of proton pump inhibitors blockers)

  • Esomeprazole (Nexium)

  • Lansoprazole( Prevacid)

  • Omeprazole (Prilosec)


Gastric anti inflammatory agents
Gastric Anti-inflammatory Agents blockers)

  • For Crohn’s disease/ulcerative colitis

  • Auto-immne rejection of one’s own intestinal lining disease

  • Ex. Mesalamine (Rowasa, Asacol)

  • Sulfasalazine (Azulfidine)

  • Oral or suppository or enema


Anti diahrreals
Anti- blockers)diahrreals

  • Kaopectate (attapulgite)

  • PeptoBismol (bismuth subsalicylate)

  • Lomotil (dipenoxulate with atropine)

  • Immodium (loperamide)


Laxatives
Laxatives blockers)

  • Colace (docusate) stool softener

  • Milk of Magnesia (magnesium hydroxide)

  • Fleet enema (sodium diphosphate) hypertonic salt solution therefore draws more water into poop and gives BM


Stimulant laxatives
Stimulant Laxatives blockers)

  • Increase peristalsis leading to BM

  • Dulcolax and Senokot, tablets or suppositories


Bulk forming laxatives
Bulk forming laxatives blockers)

  • Raise your fiber content in food which stimulates more peristalsis

  • Citrucel, Metamucil


Bowel cleansing evacuant laxatives
Bowel cleansing blockers)evacuant laxatives

  • Prior to colonoscopy for GI exams

  • Have high osmolar pressure i.e. suck fluids from your body’s bowels

  • No food intake for three hours prior to administration of meds, drink lots of water

  • Ex. GoLytely or NuLytely and Amitiza


Antiemetics
Antiemetics blockers)

  • For tx of nausea especially from narcotics and anesthetic use

  • Dramamine (dimendyrinate)

  • Chlorpromazine (Thorazine)

  • Atarax (hydroxyzine)

  • Antivert (meclizine)

  • Compazine

  • Phenergan (promethazine)

  • Tigan (trimethobenzamide)


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