gastrointestinal medications n.
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Gastrointestinal Medications. Antacids. Side effects: constipation, diarrhea Interfere with tetracycline absorption OTC meds Ex. Maalox, Mylanta (aluminum hydroxide) Milk of Magnesia (MOM) magnesium hydroxide Magnesium trisulcate ( Gelusil ). H2 Antagonists/blockers.

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antacids
Antacids
  • Side effects: constipation, diarrhea
  • Interfere with tetracycline absorption
  • OTC meds
  • Ex. Maalox, Mylanta (aluminum hydroxide)
  • Milk of Magnesia (MOM) magnesium hydroxide
  • Magnesium trisulcate (Gelusil)
h2 antagonists blockers
H2 Antagonists/blockers
  • Block gastric acid and pepsin production from stimulation by food of parietal stomach lining cells. These meds block H2 receptors in parietal cells so no acid produced
  • Usually taken at bedtime. Interfere with ASA, ethanol, caffeine and cough meds.
examples of h2 blockers
Examples of H2 blockers
  • Cimetidine (Tagamet)
  • Rantidine (Zantac)
  • Famotidine (Pepcid)
  • All are oral tablets, OTC in low doses, Rx in higher doses
proton pump inhibitors new generation antacids replacing h2 blockers
Proton Pump Inhibitors (new generation antacids replacing H2 blockers)
  • Block the ATP of the proton/acid pump of the parietal cells. Active pump in lining which makes acid is stopped by blocking access to ATP
  • Used also for GERD like H2 antagonists
ex of proton pump inhibitors
Ex. Of proton pump inhibitors
  • Esomeprazole (Nexium)
  • Lansoprazole( Prevacid)
  • Omeprazole (Prilosec)
gastric anti inflammatory agents
Gastric Anti-inflammatory Agents
  • For Crohn’s disease/ulcerative colitis
  • Auto-immne rejection of one’s own intestinal lining disease
  • Ex. Mesalamine (Rowasa, Asacol)
  • Sulfasalazine (Azulfidine)
  • Oral or suppository or enema
anti diahrreals
Anti-diahrreals
  • Kaopectate (attapulgite)
  • PeptoBismol (bismuth subsalicylate)
  • Lomotil (dipenoxulate with atropine)
  • Immodium (loperamide)
laxatives
Laxatives
  • Colace (docusate) stool softener
  • Milk of Magnesia (magnesium hydroxide)
  • Fleet enema (sodium diphosphate) hypertonic salt solution therefore draws more water into poop and gives BM
stimulant laxatives
Stimulant Laxatives
  • Increase peristalsis leading to BM
  • Dulcolax and Senokot, tablets or suppositories
bulk forming laxatives
Bulk forming laxatives
  • Raise your fiber content in food which stimulates more peristalsis
  • Citrucel, Metamucil
bowel cleansing evacuant laxatives
Bowel cleansing evacuant laxatives
  • Prior to colonoscopy for GI exams
  • Have high osmolar pressure i.e. suck fluids from your body’s bowels
  • No food intake for three hours prior to administration of meds, drink lots of water
  • Ex. GoLytely or NuLytely and Amitiza
antiemetics
Antiemetics
  • For tx of nausea especially from narcotics and anesthetic use
  • Dramamine (dimendyrinate)
  • Chlorpromazine (Thorazine)
  • Atarax (hydroxyzine)
  • Antivert (meclizine)
  • Compazine
  • Phenergan (promethazine)
  • Tigan (trimethobenzamide)