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Multi-allelic generalization of the numerically stable computation of the Exact AF calculation. Let N alt = number of alternate alleles; let. ; and let. Then in the case of diploid samples:. ( Hom Ref). (Het Ref). ( Hom Var ). (Het Var ).
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Multi-allelic generalization of the numerically stable computation of the Exact AF calculation Let Nalt = number of alternate alleles; let ; and let Then in the case of diploid samples: (Hom Ref) (Het Ref) (HomVar) (Het Var) Eric Banks, with help from Mark DePristo and Heng Li