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PET PowerPoint Presentation

PET

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PET

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    4. SENSITIVITY AND SPECIFICITY OF PET AND CT IN CANCERS Sensitivity Specificity Change in Patient (Detect cancer?) ( Detect only cancer?) Management PET CT PET CT Due to PET Lung Diagnosis 98% 67% 73% - Staging 82% 61% 91% 76% 37% Recurrence 98% 72% 92% 95% Colorectal Recurrence 93% 77% 85% 68% 31% Lymphoma Staging 89% 80% 93% 73% 21% Recurrence 83% 95% 10% Melanoma Staging 84% 88% 91% 75% 26%

    12. Average of Spatial Resolution at 1, 10, 20 cms from central axis.Average of Spatial Resolution at 1, 10, 20 cms from central axis.

    13. Sensitivity is the key parameter for finding tumors (localizing “hot spots”).Sensitivity is the key parameter for finding tumors (localizing “hot spots”).

    14. Scatter Fraction is evern better than the GSO system.Scatter Fraction is evern better than the GSO system.

    15. 2D is always better for high dose , but all your clinical work is done in the green range…..30mCi in 154lb patient injection is where our 3D and their intersect….2D is always better for high dose , but all your clinical work is done in the green range…..30mCi in 154lb patient injection is where our 3D and their intersect….

    16. 2D is always better for high dose , but all your clinical work is done in the green range…..30mCi in 154lb patient injection is where our 3D and their intersect….2D is always better for high dose , but all your clinical work is done in the green range…..30mCi in 154lb patient injection is where our 3D and their intersect….

    17. COUNTS Determine Image Quality Noise in PET images is dominated by the counting statistics of the coincidence events detected. Noise in images can be reduced by filtering, but at the cost of resolution.

    25. Sensitivity is the key parameter for finding tumors (localizing “hot spots”).Sensitivity is the key parameter for finding tumors (localizing “hot spots”).

    28. Sensitivity is the key parameter for finding tumors (localizing “hot spots”).Sensitivity is the key parameter for finding tumors (localizing “hot spots”).

    30. Technology was designed to maximize count rate… this drives better images and throughput Technology was designed to maximize count rate… this drives better images and throughput

    31. Detector Scintillator Materials – Theory “Bench” Performance of Single Crystals in Ideal Conditions Compare the three leading crystals. Look at base parameters (mauve), and effect on performance (white)Compare the three leading crystals. Look at base parameters (mauve), and effect on performance (white)

    33. Detector Scintillator Materials – Practice Performance of Clinical Scanners – Engineering Design Compare the three leading crystals. Look at base parameters (mauve), and effect on performance (white)Compare the three leading crystals. Look at base parameters (mauve), and effect on performance (white)

    34. With and Without Septa for 60 kg (130 lb) Patient Mayo Clinic - Abdomen/Liver Technology was designed to maximize count rate… this drives better images and throughput Technology was designed to maximize count rate… this drives better images and throughput

    41. Thin Slices Drive DRR Quality