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DNA Replication/ Regeneration

DNA Replication/ Regeneration. Goal of DNA Replication. Makes an _________ copy of itself (Needed for new cells produced during Mitosis). Goal of DNA Replication. Why do we need new cells? _________ Repair & _________ REGENERATION. Regeneration. Regeneration of a lost limb

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DNA Replication/ Regeneration

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  1. DNA Replication/Regeneration

  2. Goal of DNA Replication • Makes an _________ copy of itself • (Needed for new cells produced during Mitosis)

  3. Goal of DNA Replication • Why do we need new cells? • _________ • Repair & _________ • REGENERATION

  4. Regeneration • Regeneration of a lost limb • 1. De-differentiation of adult cells to stem cells • 2. Development of stem cells into new tissue

  5. When does it take place? • Regeneration/ Replication of new _________ takes place during the _________ cycle • S Phase of _________ (Mitosis)

  6. The Process of DNA Replication • 1. _________ • 2. _________ • 3. _________ • 4. _________________ • 5. _________

  7. Step 1: _________ • _________ strand uncoils • Enzyme: • DNA _________ unwinds it

  8. Step 2: Unzipping • DNA strands breaks in half (unzips) • _________ bonds are broken • Enzyme: DNA helicase breaks _________ bonds

  9. Step 2: continued • “Y” formation known as replication fork

  10. Step 3: Adding New Parts • Enzyme: DNA _________ matches original DNA strand with complementary base pairs using free nucleotides

  11. Step 3: Adding New Parts

  12. Step 3: Adding New Parts • Proofreading • Enzyme: DNA Polymerase can “backtrack” and _________ any mistakes that are made • DNA polymerase will make a mistake about 1 out of every _________ free nucleotides it matches

  13. Step 4: Two DNA molecules • Final product: 2 _________ DNA strands • One set of DNA for each cell

  14. Step 5: Recoil • DNA strand winds back up into a _________ _________

  15. DNA Replication • Entire chromosome can be replicated in about 8 hours

  16. The Future of DNA Replication/ Regeneration • Humans capable of regenerating nerve cells (cure paralysis)? • Regenerating new skin cells (slow the aging process)? • Humans capable of regenerating lost limbs (combining lizard DNA with humans)? Dr. Connors

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