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AUG - PowerPoint PPT Presentation


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Bellwork : Using the codon charts in your notes , fill in the boxes below. ** Remember to use mRNA when doing translation **. AUG. CCG. CAU. CCC. GGU. UCG. CGA. CUA. alanine. glycine. serine. aspartate / aspartic acid.

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Presentation Transcript
slide1
Bellwork: Using the codon charts in your notes, fill in the boxes below. **Remember to use mRNA when doing translation**

AUG

CCG

CAU

CCC

GGU

UCG

CGA

CUA

alanine

glycine

serine

aspartate / aspartic acid

slide4

CO: I will identify and evaluate the effects of mutations in DNA.LO: I will write notes. I will read a paragraph and fill in the missing words. I will model DNA mutations.

slide6

Cells sometimes make mistakes when copying their own DNA.These mistakes are called mutations.Mutations are changes in the genetic material.

NOTE: mutations can also be caused by environmental factors like radiation

slide8

Point Mutations: gene mutations involving changes in one ora few nucleotides - Three types of point mutations are substitutions, insertions, and deletions.

slide9

Frameshift Mutation: a nucleotide is added or deleted - the bases are still read in groups of three - those groupings are shifted for every codon that follows.

think pair share
Think-pair-share
  • Would a frame shift mutation or a point mutation cause a bigger effect in an organism? Why?
slide12

mutation

point

frameshift

protein

sickle cell anemia
Sickle Cell Anemia

These are the sickle-shaped blood cells of someone with sickle cell anemia.

Sickle cell anemia is the result of a point mutation, a change in just one nucleotide in the gene for hemoglobin. This mutation causes the hemoglobin in red blood cells to distort to a sickle shape when deoxygenated. The sickle-shaped blood cells clog in the capillaries, cutting off circulation.

Having two copies of the mutated genes cause sickle cell anemia, but having just one copy does not, and can actually protect against malaria - an example of how mutations are sometimes beneficial.

color blindness
Color Blindness
  • Most forms are caused by a point mutation on the X chromosome.

What number do you see? A color blind person won’t see anything. A color deficient person may see the number 35

achondroplasia
Achondroplasia
  • This is the most common form of dwarfism. It is caused by a substitution mutation for the gene that codes for bone growth.