Chapter 6 The Three-Dimensional Structure of Proteins. Homework: 1, 9,12 ,. Proteins: Higher Orders of Structure . The structural variety of human proteins reflects the sophistication and diversity of their biologic role
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Computers are getting better and better at interpreting X-ray diffraction patterns
Major stumbling block remains the requirement of inducing highly purified samples of the protein to crystallize
Several lines of evidence, including the ability of some crystallized enzymes to catalyze chemical reactions, indicate that the majority of the structures determined by X-ray crystallography represent the structures of proteins in free solution.