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Membrane Fluidity : Its contribution to the Dynamic N ature of the Membrane

Membrane Fluidity : Its contribution to the Dynamic N ature of the Membrane. Team Mawadda Al- Naeeli Pat Cipriano , Kim Conner, Lopa Das, Thea Edwards, Tara Luke Facilitators: Michelle Withers & Karen York. Goal.

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Membrane Fluidity : Its contribution to the Dynamic N ature of the Membrane

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  1. Membrane Fluidity : Its contribution to the Dynamic Nature of the Membrane Team Mawadda Al-Naeeli Pat Cipriano, Kim Conner, Lopa Das, Thea Edwards, Tara Luke Facilitators: Michelle Withers & Karen York

  2. Goal • Understand how the chemical structure of cell membranes underlie their function and adaptability. • u

  3. OutcomesUpon completion of this teachable unit the student will: • Explain how fluidity is changed by changes in the components of the membrane. • Predict how the lipid composition changes to maintain fluidity in extreme environments. • Practice drawing, reading and interpreting graphs.

  4. Context Introductory Biology

  5. Omega 3 Fatty Acids Have you ever heard of Omega 3 fatty acids? What are they? What are some good sources of Omega 3 fatty acids?

  6. C-C C-H

  7. Fluid nature of lipid bilayer of cell membrane Membrane proteins Mouse cell Mixed proteinsafter 1 hour Human cell Hybrid cell http://www.youtube.com/watch?v=LicQb_SnCSI

  8. A B Viscous Fluid Unsaturated hydrocarbontails Saturated hydrocarbon tails

  9. Decrease in fluidity with increase in cholesterol content

  10. Clicker Question How does an increase in temperature affect membrane fluidity? A. Increases fluidity B. Decreases fluidity C. No change

  11. Clicker Question How does an increase in temperature affect membrane fluidity? A. Increases fluidity B. Decreases fluidity C. No change

  12. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  13. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  14. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  15. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  16. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  17. Consider cold water and warm water fishes. How would membrane composition differ to maintain similar fluidity? ↑ ↓ --

  18. Using your dataset, draw a graph that would show the effects of changing temperature on membrane cholesterol and omega-3 fatty acid (unsaturated) content.

  19. Relationship between cholesterol content and habitat temperature in copepods. Hassett R P , and Crockett E L J Exp Biol 2009;212:71-77

  20. Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?1. Membranes are more rigid2. Membranes are more fluid3. Membranes maintain the same fluidity

  21. Which of the following would occur when a tropical fish suddenly finds itself in the Arctic?1. Membranes are more rigid2. Membranes are more fluid3. Membranes maintain the same fluidity4. The organism dies5. The organism survives6. Membrane maintains function7. Membrane loses function8. Lipid composition changes9. Lipid composition stays the same

  22. Which of the following would occur when considering the membrane of an organismthat…(is exposed to colder temperatures than it normally experiences?)(is exposed to warmer temperatures than it normally experiences?)(is a psychrophile?)(is a thermophile?)(has a high level of cholesterol in its membrane?)(has a low level of cholesterol in its membrane?)(contains mostly saturated fats?)(contains mostly unsaturated fats?)

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