Crucial Transition: Wet to Dry! - PowerPoint PPT Presentation

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Crucial Transition: Wet to Dry!

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  1. Lawrence F. Eichenfield, MDChief, Pediatric and Adolescent DermatologyProfessor of Pediatrics and DermatologyRady Children's Hospital and University of California, San Diego

  2. Crucial Transition: Wet to Dry!

  3. Postnatal Barrier Maturation

  4. Stratum Corneum Changes in Infants, Children, and Adolescents

  5. Elements of Innate Immune Defense

  6. The Skin Microbiome: An Emerging Contributor to Skin Defense

  7. Microbiome Development in Infant Skin

  8. Microbiome Development in Infant Skin

  9. Influence of the Innate Immune System on Skin Colonization by E. coli

  10. Microbiome Can Help Promote Innate Immunity

  11. Barrier Dysfunction and Disease States

  12. Atopic Dermatitis

  13. Filaggrin Abnormalities

  14. Filaggrin Mutation

  15. Innate Immunity and Skin Disorders

  16. Shifting Microbiomes in AD

  17. Implications for Antibiotic Use

  18. Cultural Factors Influence Skin Care, Which May Influence Skin Function

  19. Hygiene Hypothesis and Atopy?

  20. Strategy:Don’t Strip the Natural Defenses!

  21. Product Considerations

  22. Summary

  23. Abbreviaions

  24. References

  25. References

  26. References

  27. References

  28. References