1 / 8

Effect of CSF pulsations

The Effect of Nerves on Pulsatile CSF Flow and Micromixing inside the Human Spinal Cord Oct 21 st , 2010 Vu Nguyen Supervisor: Ying Hsu Advisor: Andreas A Linninger Laboratory for Product and Process Design (LPPD) University of Illinois at Chicago. t. V. t. V. Effect of CSF pulsations.

fawzia
Download Presentation

Effect of CSF pulsations

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. The Effect of Nerves on Pulsatile CSF Flow and Micromixing inside the Human Spinal CordOct 21st, 2010Vu NguyenSupervisor: Ying Hsu Advisor: Andreas A Linninger Laboratory for Product and Process Design (LPPD)University of Illinois at Chicago

  2. t V t V Effect of CSF pulsations By Dr. Madhawa

  3. Human Spinal Cord • Divided into 4 regions: cervical, thoracic, lumbar, and sacral. • Diameter of spinal canal and cord varies from the cervical to lumbar region. • There are 31 pairs of spinal nerves. • Divided into 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal nerve. • Do these nerves affect CSF flow in the spinal canal? Pic of cord diameter

  4. Goals • Study how spinal nerves would affect the pulsatile flow. • Study the pressure drop of CSF flow across the spinal canal with and without nerves • Determine whether nerves structures affect the CSF flow

  5. Construction and Simulation • Gambit and Fluent were used to construct the preliminary 2D models for a simple fluid flow. • Observations on how different operation conditions affect the model: gravity, diffusivity.

  6. 3D Model of the Spinal Cord 1 cm • Gambit was used to construct the 3D model of the thoracic region of the spinal canal. 7.5 cm Injection site 0.5 cm

  7. CSF flow inside spinal canal • Testing the effect of nerves (flow obstacles) on pressure drop With Nerves Control

  8. References • Dafny, Nachum. "Anatomy of the Spinal Cord (Section 2, Chapter 3, Part 1) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston." Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston. Web. 20 Oct. 2010. <http://neuroscience.uth.tmc.edu/s2/ii3-1.html>. • "Spine Anatomy." Zimmer.com. Web. 20 Oct. 2010. <http://www.zimmerspine.eu/z/ctl/op/global/action/1/id/9027/template/PC/navid/9989>. • H-Y Ko et al. 2004. Gross quantitative measurements of spinal cord segments in human. International Spinal Cord Society. Vol 42. 35-40. • Ikuo Aita et al. 1997. Posterior movement and enlargement of the spinal cord after cervical laminoplasty. The Journal of Bone and Joint Surgery. Vol 80-B. 33-7.

More Related