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BACKGROUND - PowerPoint PPT Presentation

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PI Names, Investigator Names, Names

Name of School, Name of School, Name of School

Step 1: Determine the mechanism of injury, including exposure to a blast/explosion (e.g., IED, RPG, mortar) and all other blows to the head (e.g., fall, sports-related Injury, physical assault, MVA).

Assessment of TBI with the BAT-L

Table 6. Identification of Possible TBI According to VA TBI Screening

Instrument Compared to BAT-L for Deployed (N=54) OEF/OIF Service Members


Mild Traumatic Brain Injury (mTBI) is the signature injury of Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) with reports of mTBI occurring in 15-22% of returning service members (Hoge et al., 2008; Terrio et al., 2009).

There are additional unique factors to OEF/OIF service members that can affect the accurate characterization and consequences of mTBI:

1. Mechanism of injury (blast vs. blunt trauma)

Cumulative number of blast exposures and/or possible brain injuries associated with longer and more frequent deployments

TBIs occurring in the context of chaos and horror leading to imprecise self-report of injury and comorbid psychiatric illness (e.g., Post-traumatic Stress Disorder)

TBIs sustained prior to and following deployment

Documentation of TBI in theater is inconsistent, non-existent, or difficult to obtain after discharge from the military. How mTBI is defined and operationalized for post-hoc classification will have significant consequences on the behavioral and neural characterization (acute & chronic) and in the determination of long-term outcome.


We have developed a semi-structured clinical interview at the VA Boston Healthcare System (joint project of the Neuropsychology Service, Polytrauma Service, and TRACTS COE) to characterize and diagnose mTBI during a service member’s lifetime.

Possible TBI is assessed during three lifetime epochs:

Pre-deployment: The three most severe TBIs sustained any time prior to deployment to OEF/OIF (including childhood).

Deployment:The three most severe TBI exposures (blast and all other); an estimate of the total number of blast exposures as a function of distance from the epicenter.

Post-deployment: The three most severe TBIs sustained any time following return to states (including active duty and retired).

Step 2: The three primary criteria for TBI (Alteration of Mental Status, Post Traumatic Amnesia, and Loss of Consciousness) are evaluated through detailed recall of the events before, during, and after the injury. Open-ended questioning is employed to prevent response bias. Other factors that might be interpreted as alterations of consciousness (e.g., chaos and confusion due to explosions, gunfire, sensory deprivation) are queried.

Agreement between measures was moderate (Kappa= 0.47).

Step 3: TBI severity is then rated according to DOD criteria and mild TBIs are graded according to a hybrid classification system.

Table 7. Comparison of TBI Diagnosis According Ohio State University TBI Identification Method vs. BAT-L for Deployed (N=60) OEF/OIF Service Members

Table 2. DOD Criteria for Severity Rating

Table 3. Hybrid Classification System for Mild TBI

DOD, 2010

Adapted from Bailes and Cantu, 2001

Step 4: The three most severe TBIs for each epoch (deployment blast, deployment other, pre-deployment, and post-deployment) are captured for data entry and reviewed at a weekly TBI diagnostic consensus meeting consisting of at least three doctoral-level Psychologists.

Agreement between measures was very good (Kappa= 0.86).

Table 8. TBI and PTSD in Deployed (N=60) OEF/OIF Service Members Using the BAT-L (categories are not mutually exclusive)


Table 4. Blast Exposure by Distance for Deployed (N=60) OEF/OIF Service Members (categories are not mutually exclusive)


*Excluding individual exposed to 500 blasts

Blast exposures are a common experience in OEF/OIF deployments, but not all result in acute TBI. Long-term consequences of multiple sub-concussive injuries are unknown.

Many veterans will present with histories that include multiple TBIs pre-, during and post-deployment.

Compared to the BAT-L, the current VA TBI Screening Instrument identified a greater number of individuals with TBI. However, eight TBI

Table 5. Consensus Diagnosis of Lifetime TBI Prevalence by Severity (N=70)


Table 1. Demographics for all participants (N=70)