safe. Not safe. . SAFE. . Concept of idiosyncratic reaction. Hypothesis:. Genetic factors largely account for an individual\'s susceptibility to an idiosyncratic toxicity . Therefore, molecular diagnostics could identify patients at risk for toxicity.. Science:294,2274,2001. FDA Working Group on Pharmacogenetics and Pharmacogenomics Subcommittee of the Advisory Committee for Pharmaceutical Science, October 23, 2002. .
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