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Imaging with Positron Emission Tomography/ Computed Tomography ( PET/CT). Lisa Rhoden (RT)(R) B.S. CNMT. PET. PET permits investigation and comparison of events occurring at the molecular and cellular level. This data is not attainable by other modalities .

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imaging with positron emission tomography computed tomography pet ct

Imaging with Positron Emission Tomography/ Computed Tomography (PET/CT)

Lisa Rhoden (RT)(R) B.S. CNMT

slide2
PET
  • PET permits investigation and comparison of events occurring at the molecular and cellular level.
    • This data is not attainable by other modalities.
  • PET is especially useful in the detection of cancer, coronary heart disease, and brain disease.
  • The basis of PET is the positron
    • The positron is a positively charged beta particle emitted from neutron-poor radionuclides.
    • The result of this emission are annihilation photons that create 2 gamma rays of exactly 511 keV each, at 180 degrees to each other.
slide3

Positron Decay

  • Annihilation - two photons

511 keV

-

Positronium

180o

+

511 keV

For more on Positron Decay click

pet ct vs pet
PET/CT vs. PET
  • The ability to have the CT localization makes interpretations more accurate
  • PET/CT has advantages to the patient in making the acquisition time shorter
  • There is more accurate attenuation correction with PET/CT

PET/CT Machine

protocol dose receiving
Protocol:Dose Receiving
  • Upon receiving a dose shipment from the pharmacy, the technologist must check it in
  • This includes measuring the radioactivity in mR at the surface of the box and at one meter away.
  • All measurements are recorded and kept
protocol patient prep at uams
Protocol: Patient Prep (at UAMS)
  • Patient is to be held NPO (with the exception of water) a minimum of six hours prior to injection time
  • No insulin or Dextrose-5 should be given to the patient for a minimum of six hours prior to injection
  • The patient may receive 5-10 mg of Valium before the injection is given
  • The patient should be made comfortable and relaxed

Did the patient follow the prep correctly?

YES NO

protocol blood glucose level
Protocol: Blood Glucose Level
  • A blood glucose level will be obtained prior to injection and recorded
  • Optimum blood glucose level is below 150 mg/dL

Select the patient’s blood glucose level

Below 150 mg/dL

Above 150 mg/dL

next assay the dose
Next: Assay the Dose
  • The tech will then do background counts and a wipe test
  • Next the dose will be assayed, or measured for radioactivity in the dose calibrator
protocol isotope injection
Protocol: Isotope Injection

An IV will be started and used to administer the radioactive tracer

Patient will wait 2-3 hours to allow the isotope to be taken into the cells

protocol cont
Protocol Cont.
  • Patient will drink approximately 300 cc of contrast containing Omnipaque (iohexol) 300 mgI/ml
  • Remove metallic objects
  • Empty bladder
protocol cont1
Protocol Cont.
  • Position for scanning
  • Patient position will be determined based on area being scanned
breast cancer
Breast Cancer

CT

PET

Fused

slide15

Review Basic PET Process

Tracer

injection &

data acquisition

Isotope

production

(cyclotron)

Data

synthesis

Tracer

labeling

(radiochemistry)

Image

reconstruction

Interpretation

thank you for your time
Thank you for your time

Questions?

Want more?

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